产品名称
MILLIPLEX® 人MMP磁珠板2-免疫学多重检测,
description
Configurable Human MMP 5-Plex Panel
Quality Segment
species reactivity
human
packaging
pkg of 1 ea
manufacturer/tradename
Milliplex®
assay range
accuracy: 72-98%, standard curve range: 14-10,000 pg/mL
(MMP-9), standard curve range: 27-20,000 pg/mL
(MMP-1), standard curve range: 27-20,000 pg/mL
(MMP-10), standard curve range: 548-400,000 pg/mL
(MMP-7), standard curve range: 68-50,000 pg/mL
(MMP-2)
technique(s)
multiplexing: suitable
input
cell culture supernatant(s)
plasma
urine
serum
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
General description
MMPs (matrix metalloproteinases), a family of zinc proteases responsible for the breakdown of extracellular matrix (ECM), play a key role in normal physiological processes, such as embryonic development and tissue morphogenesis, tissue and bone remodeling, wound healing, and angiogenesis. These processes rely on MMPs′ role in the cleavage of cell surface receptors, the release of apoptotic ligands, cell proliferation and differentiation, and chemokine activity modulation. Similar in structure, MMPs are synthesized and secreted as inactive pro-enzymes that require proteolytic cleavage for activation. This process can be mediated by serine proteases or other MMPs. An increase in MMP expression occurs in response to a wide range of stimuli, including adhesion molecules, growth factors, cytokines, and hormones. Regulation of MMP activity is controlled primarily by TIMPs (tissue inhibitors of metalloproteinases). Therefore, disruption of the MMP/TIMP balance can result in arthritis, cardiovascular disease and tumor growth and metastasis.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 5 analytes in human serum, plasma, urine, and cell culture supernatants.
Analytes included: MMP-1, MMP-2, MMP-7, MMP-9, MMP-10
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Analytes included: MMP-1, MMP-2, MMP-7, MMP-9, MMP-10
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
- Comprehensive MMP Coverage: Key MMPs involved in inflammation, cardiovascular disease, and cancer research for complete MMP/TIMP pathway analysis.
- Advanced Multiplex Technology: Luminex® xMAP® magnetic bead platform quantitates 5 critical MMPs (MMP-1, -2, -7, -9, -10) simultaneously in one well with superior speed and sensitivity in a single day.
- Flexible Design: Configure your panel by selecting specific analytes and scale from small studies to large trials, supporting diverse inflammation and immunology research applications.
- Sample Versatility: Compatible with human serum, plasma, urine, tissue/cell lysates, and culture supernatants using optimized dilutions that conserves sample volume for research applications.
- Research Applications: Target disease-relevant biomarkers in arthritis, cardiovascular disease, and cancer research to support biomarker discovery, mechanistic studies, and translational research programs.
- Research-Grade Quality: Verified for research use with standardized protocols, comprehensive technical support, and quality systems designed for multi-laboratory research collaborations.
Legal Information
Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Still not finding the right product?
Explore all of our products under MILLIPLEX® 人MMP磁珠板2-免疫学多重检测
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
target_organs
Respiratory Tract
存储类别
10 - Combustible liquids
wgk
WGK 3