HNDG2MAG-36K
MILLIPLEX® Human Neurodegenerative Disease Magnetic Bead Panel 2 - Neuroscience Multiplex Assay
The analytes available for this multiplex kit are: α1-Antitrypsin, Complement C4, CRP, MIP-4, PEDF, SAP.
Quality Level
species reactivity
human
manufacturer/tradename
Milliplex®
assay range
accuracy: 84%
(SAP)
accuracy: 88%
(Complement C4)
accuracy: 92%
(α-1-Antitrypsin)
accuracy: 92%
(PEDF)
accuracy: 95%
(MIP-4)
standard curve range: 0.05-200 ng/mL
(PEDF)
standard curve range: 0.10-50 ng/mL
(CRP)
standard curve range: 0.12-500 ng/mL
(SAP)
standard curve range: 0.24-1,000 ng/mL
(α-1-Antitrypsin)
standard curve range: 0.24-1,000 ng/mL
(Complement C4)
standard curve range: 4.88-20,000 ng/mL
(MIP-4)
technique(s)
multiplexing: suitable
detection method
fluorometric (Luminex xMAP)
shipped in
wet ice
Related Categories
General description
Neurodegenerative disease is a condition characterized by the deterioration of neurons or their myelin sheath over time in the brain and/or spinal cord. These neurons are responsible for such everyday activities as processing sensory information, making decisions, and controlling movement. Because these cells are not easily regenerated, excessive cumulative damage can lead to age-related diseases such as Alzheimer′s and Parkinson′s disease, as well as other conditions such as amyotrophic lateral sclerosis (ALS) and epilepsy. These disorders are devastating and expensive, both on a personal and global level, and as population demographics continue to change, a therapeutic solution is critical. Consequently, research is underway to identify biomarkers that will help scientists not only understand the pathogenesis of neurodegenerative disease, but also identify people with these disorders before the onset of symptoms and potentially provide new therapeutic tools.
Panel Type: Neuroscience
Specificity
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Application
- Analytes: α1-Antitrypsin, Complement C4, CRP, MIP-4, PEDF, SAP
- Recommended Sample type: serum, plasma and CSF
- Recommended Sample dilution: 1:2,000 diluted serum/plasma or 1:20 diluted CSF
- Assay Run Time: Overnight
- Research Category: Neuroscience
- Research Subcategory: Alzheimer′s Disease Nervous System
Features and Benefits
Packaging
Storage and Stability
Other Notes
Legal Information
Disclaimer
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
Target Organs
Respiratory Tract
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Regulatory Information
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