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Merck
CN

LP1

VLDL, human

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About This Item

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.41
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biological source

human

Quality Level

Assay

≥95% (of total lipoprotein content, electrophoresis)

form

liquid

manufacturer/tradename

Chemicon®

shipped in

wet ice

General description

DENSITY:

0.95-1.006 g/mL
Product Source: Human plasma tested negative for HBsAg and HIV-I, HIV-II, HBc and Hepatitis C antibodies. All blood products should be treated as potentially infectious.
VLDL is isolated from fresh human plasma containing EDTA and sodium citrate by sequential isopycnic ultracentrifugation at the lower and upper density limits of the specified density range (Havel et al., 1955). Density adjustments are performed with solid KBr. VLDL is washed by centrifugation at the upper density limit to ensure removal of higher density proteins.

Physical form

Liquid in 150 mM NaCl, pH 7.4 with 0.01% EDTA. Filtered to sterility using 0.2 micron filter in a sterile vial.

COMPOSITION:

88-95% lipid, 5-12% protein

Preparation Note

Maintain at 2-8°C for up to four weeks. DO NOT FREEZE. Freezing may cause denaturation.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Nicotine increases dopamine transporter function in rat striatum through a trafficking-independent mechanism.
Lisa S Middleton,Subbu Apparsundaram,Kelley A King-Pospisil,Linda P Dwoskin
European Journal of Pharmacology null
Gender-specific effect of Mthfr genotype and neonatal vigabatrin interaction on synaptic proteins in mouse cortex.
Elinor Blumkin,Tamar Levav-Rabkin,Osnat Melamed,Dalia Galron,Hava M Golan
Neuropsychopharmacology null
Increased levels of Homer1b/c and Shank1a in the post-synaptic density of spinal dorsal horn neurons are associated with neuropathic pain in rats.
Gordana Miletic,Takako Miyabe,Kara J Gebhardt,Vjekoslav Miletic
Neuroscience Letters null
Striatal enriched phosphatase 61 dephosphorylates Fyn at phosphotyrosine 420.
Tri-Hung Nguyen,Jian Liu,Paul J Lombroso
The Journal of Biological Chemistry null
Gordana Miletic et al.
Pain, 149(1), 152-159 (2010-02-23)
Plasticity in the spinal dorsal horn may contribute to the development of pain following peripheral nerve injury. Shank proteins are a constituent family of the post-synaptic density (PSD), and they may play a role in synaptic plasticity through activity-dependent synaptic

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