MAB11004
Anti-hnRNP Q Antibody, clone 7A11.2
clone 7A11.2, from mouse
Synonym(s):
heterogeneous nuclear ribonucleoprotein Q-like, Synaptotagmin-binding, cytoplasmic RNA-interacting protein, Glycine- and tyrosine-rich RNA-binding protein, GRY-RBP, NS1-associated protein 1
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
7A11.2, monoclonal
Application:
ICC, WB
Citations:
4
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
7A11.2, monoclonal
species reactivity
mouse, rat, human
technique(s)
immunocytochemistry: suitable, western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... SYNCRIP(10492)
General description
Heterogeneous nuclear ribonucleoprotein Q, commonly refered to as hnRNP Q, can be found as three different isoforms derived from alternative splicing of a single gene. This RNA binding protein is implicated in control of mRNA precursor splicing for the survival of motor neurons (SMN) protein. Loss-of-function mutations of SMN are linked to spinal muscular atrophy (SMA) a common neurodegenerative disease. It has been shown that hnRNP Q proteins interact with SMN, and this is interacton is required for efficient pre-mRNA splicing in vitro. Current data suggests that hnRNP Q is a splicing modulator of SMN.
~59 observed. Mulitple isoforms may be observed in some lysates.
Immunogen
Full length recombinant protein corresponding to human hnRNPQ.
Application
Anti-hnRNP Q Antibody, clone 7A11.2 is a Mouse Monoclonal Antibody for detection of hnRNP Q also known as heterogeneous nuclear ribonucleoprotein Q-like & has been validated in WB, ICC.
Western Blot Analysis: 1 µg/mL from a representative lot detected hnRNP Q on 10 µg of PC-12 and HEK293 cell lysate.
Immunocytochemistry Analysis: 1:500 dilution from a representative lot detected hnRNP Q in NIH/3T3, A431, and HeLa cells.
Immunocytochemistry Analysis: 1:500 dilution from a representative lot detected hnRNP Q in NIH/3T3, A431, and HeLa cells.
Physical form
Format: Purified
Analysis Note
Evaluated by Western Blot in NIH/3T3 cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected hnRNP Q on 10 µg of NIH/3T3 cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected hnRNP Q on 10 µg of NIH/3T3 cell lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB11004 | 04053252750229 |