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Merck
CN

MAB1155

Anti-Interferon-α/β Receptor Chain 2 Antibody, clone MMHAR-2

clone MMHAR-2, Chemicon®, from mouse

Synonym(s):

CD118

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
MMHAR-2, monoclonal
Application:
FACS, IHC, IP
Citations:
25
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

MMHAR-2, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable

isotype

IgG2a

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... IFNA1(3439)

Immunogen

Human Interferon alpha/beta Receptor Chain 2

Application

Anti-Interferon-α/β Receptor Chain 2 Antibody, clone MMHAR-2 is an antibody against Interferon-α/β Receptor Chain 2 for use in FC, IP, IH.
Biological Studies

Immunoprecipitation: (1-5 μg/mL)

Immunohistochemistry: (1μg/mL)

Flow cytometry: (1 μg/10 mL - block cells with 50% human AB serum)

Optimal working dilutions must be determined by end user.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors

Biochem/physiol Actions

Reacts with Human Interferon alpha/beta Receptor Chain 2 (CD118). Antibody neutralizes human interferon alpha receptor, interacts with extracellular domain, binds to human interferon alpha receptor with high affinity, and blocks biological action of Type I interferons.

Physical form

Format: Purified
Purified immunoglobulin. Liquid in PBS containing 0.1% bovine serum albumin (BSA).

Preparation Note

Maintain frozen at -20°C or below for retention of full activity, for up to 12 months. When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Chlamydia trachomatis-infected epithelial cells and fibroblasts retain the ability to express surface-presented major histocompatibility complex class I molecules.
Kagebein, D; Gutjahr, M; Gro?e, C; Vogel, AB; Rodel, J; Knittler, MR
Infection and Immunity null
Ting Zhang et al.
Hepatology (Baltimore, Md.), 42(4), 819-827 (2005-09-22)
The chronicity of hepatitis C virus (HCV) infection raises the question of how HCV is able to persist in hepatic cells. We show that human primary hepatocytes and human hepatic cell lines (Huh7 and HepG2) spontaneously produce interferon (IFN)-alpha that
Aura Muntasell et al.
Frontiers in immunology, 4, 40-40 (2013-02-27)
Natural killer (NK) cells play an important role in the defense against viral infections. Activation of resting NK cells is tightly controlled by the balance of surface inhibitory and activating receptors and aided by cytokines released by accessory cells along



Global Trade Item Number

SKUGTIN
MAB115504053252663758