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About This Item
UNSPSC Code:
12352203
NACRES:
NA.46
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
HP6023, monoclonal
Application:
ELISA, RIA, WB
Citations:
4
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
secondary antibodies
clone
HP6023, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, radioimmunoassay: suitable, western blot: suitable
isotype
IgG3
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... FCGR2B(2213)
Immunogen
Epitope: Fc fragment
Application
Mouse anti-Human IgG4 Antibody, clone HP6023, Fc is an antibody against Human IgG4 for use in ELISA, RIA & WB.
Research Category
Secondary & Control Antibodies
Secondary & Control Antibodies
Research Sub Category
Fragment Specific Secondary Antibodies
Fragment Specific Secondary Antibodies
This antibody employed as both a capture antibody and a detection antibody for human IgG subclass 4 in enzyme linked immunosorbent assays, radio-immunoassay and EIA affinity immunoblots (Papadea et al., 1985; Hamilton, et al., 1987).
Final working dilutions must be determined by end user.
Final working dilutions must be determined by end user.
Biochem/physiol Actions
Human IgG4 Fc. ELISA Specificity: (Hamilton et al., 1987) human IgG subclass 1- 0.08% human IgG subclass 2 - 0.01% human IgG subclass 3 - 0.04% human IgG subclass 4-100% Isoelectric Focusing: mean pI 7.7
Physical form
Format: Purified
Purified immunoglobulin. 0.02MPB+ 0.25M NaCl , Ph=7.6, 0.1% soduim azide.
Preparation Note
Maintain at 2 -8°C for up to one year in undiluted aliquots.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: 411493-200UG
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Storage Class
12 - Non Combustible Liquids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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F Brière et al.
The Journal of experimental medicine, 179(2), 757-762 (1994-02-01)
During antigen-induced immune responses, human B cells switch isotype from immunoglobulin M (IgM)-IgD to IgG1-4, IgA1-2, or IgE. In the human, no cytokines have yet been demonstrated to act as switch factors for IgG1, IgG2, and IgG3. In this paper
Katherine A McLaughlin et al.
Journal of immunology (Baltimore, Md. : 1950), 183(6), 4067-4076 (2009-08-19)
Multiple sclerosis (MS) typically manifests in early to mid adulthood, but there is increasing recognition of pediatric-onset MS, aided by improvements in imaging techniques. The immunological mechanisms of disease are largely unexplored in pediatric-onset MS, in part because studies have
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB1312 | 04053252668272 |