MAB1522
Anti-Actin Antibody, smooth muscle γ & α actin,
CHEMICON®, mouse monoclonal, CGA7
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
CGA7, monoclonal
Species reactivity:
human, rat, chicken, rabbit, monkey
Application:
IHC (p), WB
Citations:
30
Product Name
Anti-Actin Antibody, smooth muscle γ & α actin, clone CGA7, ascites fluid, clone CGA7, Chemicon®
Quality Level
biological source
mouse
antibody form
ascites fluid
clone
CGA7, monoclonal
species reactivity
human, rat, chicken, rabbit, monkey
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, western blot: suitable
isotype
IgG2a
NCBI accession no.
shipped in
dry ice
target post-translational modification
unmodified
Immunogen
Chicken gizzard actin
Epitope: smooth muscle gamma & alpha actin
Application
Detect Actin using this Anti-Actin Antibody, smooth muscle γ & α actin, clone CGA7 validated for use in WB, IH, IH(P).
Western Blot: 1:1000 (approximately 43 kDa)
Immunohistochemistry (paraffin, formalin, deparaffinized methacarn-fixed tissue: 1:10,000 or alcohol fixation)
Optimal dilutions must be determined by the end user.
Immunohistochemistry (paraffin, formalin, deparaffinized methacarn-fixed tissue: 1:10,000 or alcohol fixation)
Optimal dilutions must be determined by the end user.
Biochem/physiol Actions
Antibody recognizes actin isotypes alpha and gamma of smooth muscle cells, but not skeletal or cardiac muscle cells. Reactive with myoepithelium, but nonreactive with other mesenchymal and all epithelial cells. The antibody labels eiomyosarcomas and leiomyomas but does not react with other neoplasms such as carcinomas or lymphoma.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Receptor-operated Ca2+ entry mediated by TRPC3/TRPC6 proteins in rat prostate smooth muscle (PS1) cell line.
S Thebault, A Zholos, A Enfissi, C Slomianny, E Dewailly, M Roudbaraki, J Parys, Natalia Prevarskaya
Journal of Cellular Physiology null
Brian J Leibowitz et al.
Nature communications, 5, 3494-3494 (2014-03-19)
The role of bone marrow (BM) and BM-derived cells in radiation-induced acute gastrointestinal (GI) syndrome is controversial. Here we use bone marrow transplantation (BMT), total body irradiation (TBI) and abdominal irradiation (ABI) models to demonstrate a very limited, if any
Xin Yao et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 13(1), 161-169 (2007-01-04)
Intratumoral microvascular density (MVD) has been controversial as an indicator of prognosis in clear cell renal cell carcinoma (CCRCC). Classification of the intratumoral blood vessels based on differential expressions of blood vessel markers has not been correlated with patient prognosis
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB1522 | 04053252613173 |