MAB1587
Anti-Glutamate Transporter Antibody, neuronal, clone 4D6.2
clone 4D6.2, Chemicon®, from mouse
Synonym(s):
EAAT3
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
4D6.2, monoclonal
Application:
IHC, WB
Citations:
8
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
4D6.2, monoclonal
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... SLC1A1(6505)
Immunogen
C-terminus peptide (KDKSDTISFTQTSQF) (Catalog Number AG372).
Application
Anti-Glutamate Transporter Antibody, neuronal, clone 4D6.2 is an antibody against Glutamate Transporter for use in IH & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
Western blot: 1-2 μg/mL
Immunohistochemistry: 1-2 μg/mL
Optimal working dilutions must be determined by end user.
EAAC1 is approximately 66-70kDa; the protein can form homomultimers during preparation as well, thus often times large 200-220kDa bands can also be seen.
Immunohistochemistry: 1-2 μg/mL
Optimal working dilutions must be determined by end user.
EAAC1 is approximately 66-70kDa; the protein can form homomultimers during preparation as well, thus often times large 200-220kDa bands can also be seen.
Biochem/physiol Actions
Glutamate Transporter EAAC1.
Based on protein sequence the antibody is expected to react with mouse, bovine and rabbit.
Based on protein sequence the antibody is expected to react with mouse, bovine and rabbit.
Physical form
Format: Purified
Purified immunoglobulin. Liquid in 0.02M Phosphate buffer, 0.25M NaCl, pH 7.6 with 0.1% sodium azide.
Preparation Note
Maintain at 2-8°C for up to six months.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Related Content
Clozapine-induced reduction of glutamate transport in the frontal cortex is not mediated by GLAST and EAAC1.
M Melone et al.
Molecular psychiatry, 8(1), 12-13 (2003-01-31)
Bárbara Coimbra et al.
Nature communications, 10(1), 4138-4138 (2019-09-14)
The laterodorsal tegmentum (LDT) is associated with reward considering that it modulates VTA neuronal activity, but recent anatomical evidence shows that the LDT also directly projects to nucleus accumbens (NAc). We show that the majority of LDT-NAc inputs are cholinergic
M C Medrano et al.
British journal of pharmacology, 169(8), 1781-1794 (2013-05-04)
Excitatory amino acid transporters (EAATs) in the CNS contribute to the clearance of glutamate released during neurotransmission. The aim of this study was to explore the role of EAATs in the regulation of locus coeruleus (LC) neurons by glutamate. We
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB1587 | 04053252318764 |