MAB1876
Anti-Integrin αVβ6 Antibody
CHEMICON®, mouse monoclonal, 27.1 (VNR-1)
Synonym(s):
CD51/CD61, VNR-1
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
27.1 (VNR-1), monoclonal
Species reactivity:
human
Application:
IF, IP
Citations:
4
Product Name
Anti-Integrin αVβ3 Antibody, clone 27.1 (VNR-1), clone 27.1 (VNR-1), Chemicon®, from mouse
biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
27.1 (VNR-1), monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunofluorescence: suitable, immunoprecipitation (IP): suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... ITGAV(3685)
Application
Anti-Integrin αVβ3 Antibody, clone 27.1 (VNR-1) detects level of Integrin αVβ3 & has been published & validated for use in IF & IP.
Immunohistochemistry: 4-10% formalin fixed frozen tissues (short fixation times, 10 minutes room temperature) only; not effective on paraffin embedded tissues
Immunoprecipitation
Functional blocking: Competes with clone LM609 for integrin function blocking.
Optimal working dilutions must be determined by end user.
Immunoprecipitation
Functional blocking: Competes with clone LM609 for integrin function blocking.
Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
Biochem/physiol Actions
Reacts with the human integrin alphaVbeta3. Shown to be specific for alphaVbeta3 by Loftus JC et al (1990) Science 249:915-918.
Physical form
Format: Purified
Protein A purified mouse immunoglobulin in liquid in 0.02M PB, pH 7.6, 0.25M NaCl containing 0.1% sodium azide.
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Storage Class
12 - Non Combustible Liquids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Dake Hao et al.
Frontiers in bioengineering and biotechnology, 8, 890-890 (2020-08-28)
Endothelial cell (EC) transplantation via injectable collagen hydrogel has received much attention as a potential treatment for various vascular diseases. However, the therapeutic effect of transplanted ECs is limited by their poor viability, which partially occurs as a result of
Handong Ma et al.
Cell reports, 30(3), 793-806 (2020-01-23)
Periostin is a multifunctional extracellular matrix protein involved in various inflammatory diseases and tumor metastasis; however, evidence regarding whether and how periostin actively contributes to inflammation-associated tumorigenesis remains elusive. Here, we demonstrate that periostin deficiency significantly inhibits the occurrence of
Kouki Morizono et al.
Journal of virology, 88(8), 4275-4290 (2014-01-31)
We recently demonstrated that a soluble protein, Gas6, can facilitate viral entry by bridging viral envelope phosphatidylserine to Axl, a receptor tyrosine kinase expressed on target cells. The interaction between phosphatidylserine, Gas6, and Axl was originally shown to be a
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB1876 | 04053252616778 |