MAB2052
Anti-Disialoganglioside GD2 Antibody, clone 14G2a
clone 14.2Ga, Chemicon®, from mouse
Synonym(s):
Anti-GD2 Antibody, Clone 14G2a Anti-GD2, GD2 Detection Antibody
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
14.2Ga, monoclonal
Species reactivity:
human
Application:
FACS, IF, IHC
Citations:
10
biological source
mouse
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
14.2Ga, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable
isotype
IgG2a
shipped in
wet ice
target post-translational modification
unmodified
Application
Anti-Disialoganglioside GD2 Antibody, clone 14G2a detects level of Disialoganglioside GD2 & has been published & validated for use in FC, IF, IH.
Immunohistochemistry (frozen tissue sections)(Cheresh et al., 1986)
Immunofluorescence of cells in culture
Flow cytometry: 1-2 μg per 10E6 cells
Cytotoxicity for GD2 positive cells (Mujoo et al., 1987, 1989)
Optimal working dilutions must be determined by end user.
Immunofluorescence of cells in culture
Flow cytometry: 1-2 μg per 10E6 cells
Cytotoxicity for GD2 positive cells (Mujoo et al., 1987, 1989)
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
Reacts specifically with human GD2 ganglioside.
Physical form
Cell culture supernatant in 0.02M PB, pH 7.6, 0.25M NaCl containing 0.1% Sodium Azide
Format: Purified
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Storage Class
12 - Non Combustible Liquids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Related Content
Patrizia Garbati et al.
International journal of molecular sciences, 22(13) (2021-07-03)
High-risk neuroblastoma (HR-NB) still remains the most dangerous tumor in early childhood. For this reason, the identification of new therapeutic approaches is of fundamental importance. Recently, we combined the conventional pharmacological approach to NB, represented by cisplatin, with fendiline hydrochloride
Christian M Seitz et al.
Oncoimmunology, 9(1), 1683345-1683345 (2020-02-01)
Expression of the disialoganglioside GD2 has been identified as a marker antigen associated with a breast cancer stem-like cell (BCSC) phenotype. Here, we report on the evaluation of GD2 as a BCSC-specific target antigen for immunotherapy. GD2 expression was confirmed
Martin V Kolev et al.
Journal of immunology (Baltimore, Md. : 1950), 184(11), 6035-6042 (2010-04-28)
Tumor cells escape clearance by complement by abundantly expressing CD59 and other membrane complement regulators. Recently, we designed a peptide derived from the neural-restrictive silencer factor (REST), REST68, which we showed to inhibit expression of CD59 in tumors lacking the
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB2052 | 04053252615207 |