MAB338
Anti-Ciliary Neurotrophic Factor Antibody, clone 4-68
clone 4-68, Chemicon®, from mouse
Synonym(s):
CNTF
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
4-68, monoclonal
Application:
IHC, WB
Citations:
17
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
4-68, monoclonal
species reactivity
mouse, rat, human, monkey
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... CNTF(1270)
Immunogen
Purified ciliary neurotrophic factor from rat sciatic nerve.
Application
Immunohistochemistry: 10-20 μg/mL on frozen sections of rat sciatic nerve perfused and counter-fixed with 4% paraformaldehyde (Stockli et al., 1991).
Western blotting: 10 μg/mL (Stockli et al., 1991)
Optimal working dilutions must be determined by the end user.
Western blotting: 10 μg/mL (Stockli et al., 1991)
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
Neurochemistry & Neurotrophins
This Anti-Ciliary Neurotrophic Factor Antibody, clone 4-68 is validated for use in WB, IH for the detection of Ciliary Neurotrophic Factor.
Biochem/physiol Actions
Ciliary neurotrophic factor. Detects a 22 kD band in Western blots of rat sciatic nerve extract.
Physical form
Format: Purified
Liquid in 0.02M phosphate buffer, 0.25M NaCl with 0.1% sodium azide, pH 7.6.
Preparation Note
Maintain at 2-8°C for up to 6 months. Avoid repeated freeze/thaw cycles.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Storage Class
12 - Non Combustible Liquids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Related Content
Cuihong Jia et al.
Glia, 66(11), 2456-2469 (2018-12-01)
Astrocyte-derived ciliary neurotrophic factor (CNTF) promotes adult subventricular zone (SVZ) neurogenesis. We found that focal adhesion kinase (FAK) and JNK, but not ERK or P38, repress CNTF in vitro. Here, we defined the FAK-JNK pathway and its regulation of CNTF
Milena Girotti et al.
Neuropharmacology, 160, 107791-107791 (2019-09-26)
Deficits in cognitive flexibility, i.e. the ability to modify behavior in response to changes in the environment, are present in several psychiatric disorders and are often refractory to treatment. However, improving treatment response has been hindered by a lack of
Cuihong Jia et al.
Stem cell research, 49, 102061-102061 (2020-11-02)
Constant neuroregeneration in adult olfactory epithelium maintains olfactory function by basal stem cell proliferation and differentiation to replace lost olfactory sensory neurons (OSNs). Understanding the mechanisms regulating this process could reveal potential therapeutic targets for stimulating adult olfactory neurogenesis under
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB338 | 08436037124907 |