MAB3478
Anti-1-cys Peroxiredoxin Antibody, clone 8H11
ascites fluid, clone 8H11, Chemicon®
Synonym(s):
aiPLA2, Peroxiredoxin 6, Non-selenium Glutathione Peroxidase
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
8H11, monoclonal
Application:
ICC, IHC, WB
Citations:
2
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
8H11, monoclonal
species reactivity
human, rat
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable
isotype
IgM
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... PRX(57716)
General description
1-Cys-Peroxiredoxin is a cytosolic protein that is involved in the regulation of cellular redox potential. 1-Cys peroxiredoxin is a bifunctional enzyme with glutathione peroxidase and phospholipase A2 activities (Chen, 2000). It can reduce hydrogen peroxide, short chain fatty acids, and phospholipid hydroperoxides and is believed to play a role in phospholipid turnover as well as in the protection against oxidative injury.
Immunogen
Recombinant human 1-Cys peroxiredoxin.
Application
Detect 1-cys Peroxiredoxin using this Anti-1-cys Peroxiredoxin Antibody, clone 8H11 validated for use in WB, IC, IH.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Oxidative Stress
Oxidative Stress
Western blot on rat lung lysate (24 kDa) or recombinant human protein.
Immunohistochemistry on 4% paraformaldehyde fixed rat lung tissue.
Immunocytochemistry on rat type II alveolar epithelial cells.
Optimal working dilutions must be determined by the end user.
Immunohistochemistry on 4% paraformaldehyde fixed rat lung tissue.
Immunocytochemistry on rat type II alveolar epithelial cells.
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
1-Cys-Peroxiredoxin (Prx VI).
Physical form
Ascites fluid. Liquid.
Preparation Note
Maintain at -20°C in undiluted aliquots up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Seunghyi Kook et al.
The Journal of biological chemistry, 291(16), 8414-8427 (2016-02-26)
The Hermansky Pudlak syndromes (HPS) constitute a family of disorders characterized by oculocutaneous albinism and bleeding diathesis, often associated with lethal lung fibrosis. HPS results from mutations in genes of membrane trafficking complexes that facilitate delivery of cargo to lysosome-related
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB3478 | 04053252360589 |