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Merck
CN

MAB413

Anti-Interferon-α Antibody, clone ST126

ascites fluid, clone ST126, Chemicon®

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
ST126, monoclonal
Application:
Neutral
Citations:
3

Key Documents

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biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

clone

ST126, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

neutralization: suitable

isotype

IgG2b

NCBI accession no.

NM_000605.2

UniProt accession no.

P01563

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Immunogen

Human alpha-interferon

Application

Anti-Interferon-α Antibody, clone ST126 detects level of Interferon-α & has been published & validated for use in NEUT.
Neutralizes anti-viral activity of interferon.

Dilute with buffer pH 7.5 - 8.0 to desired working volumes. Final working dilutions must be determined by end user. For extensive dilution use protein-containing or other stabilizing medium.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors

Biochem/physiol Actions

Human interferon-alpha sub-species. Distinguishes between sub-species of human alpha-interferon. Can be used to detect interferon oligomers.

Physical form

Liquid, no preservatives.

Preparation Note

Maintain at -20°C for up to 12 months.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Monoclonal antibodies that distinguish between subspecies of human interferon-alpha and that detect interferon oligomers.
Shearer, M, et al.
Journal of immunology (Baltimore, Md. : 1950), 133, 3096-3101 (1984)
Marlena M Westcott et al.
Journal of virology, 89(15), 7944-7954 (2015-05-23)
Oncolytic viruses (OV) preferentially kill cancer cells due in part to defects in their antiviral responses upon exposure to type I interferons (IFNs). However, IFN responsiveness of some tumor cells confers resistance to OV treatment. The human type I IFNs

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