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Merck
CN

MAB4140

Anti-MDR3 Antibody, clone P3 II-26

culture supernatant, clone P3 II-26, Chemicon®

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
P3 II-26, monoclonal
Species reactivity:
human
Application:
ICC, IHC, WB
Citations:
9
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biological source

mouse

Quality Segment

antibody form

culture supernatant

antibody product type

primary antibodies

clone

P3 II-26, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable

isotype

IgG2b

suitability

not suitable for immunohistochemistry (Paraffin)

NCBI accession no.

UniProt accession no.

shipped in

wet ice

Gene Information

human ... ABCB4(5244)

Immunogen

Mab was selected after immunization with a fusion protein consisting of Gluthatione-S-Transferase and a fragment of MDR3 P-gp comprising aa 629-692.

Application

Anti-MDR3 Antibody, clone P3 II-26 is an antibody against MDR3 for use in WB, IC, IH.
Western Blotting: MDR3 is a 140 kDa protein.

Immunocytochemistry: 1:20 - 1:50 on acetone-fixed cytospin preparations

Immunohistochemistry: 1:20 on acetone-fixed frozen sections

Not suitable for paraffin-embedded tissues

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

This antibody reacts with an internal epitope of MDR3 P-gp. It does not cross-react with the human MDR1 P-gp. It has been reported that this clone also cross reacts with mouse MDR2 Pgp {Kok et al 2003 {http://www.biochemj.org/bj/369/0539/3690539.pdf}.

Preparation Note

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

10 - Combustible liquids

wgk

WGK 2



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKUGTIN
MAB414004053252578908