MAB4350
Anti-BMP-7 Antibody, clone 2A10
clone 2A10, from mouse
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
2A10, monoclonal
Application:
IHC, WB
Citations:
4
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
2A10, monoclonal
species reactivity
mouse, human
technique(s)
immunohistochemistry: suitable, western blot: suitable
input
sample type mesenchymal stem cell(s)
isotype
IgG1κ
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... BMP7(655)
mouse ... Bmp7(12162)
General description
46 kDa
Bone morphogenetic protein-7 (BMP-7), also known as osteogenic protein-1, is a member of the TGF- superfamily, and is widely expressed during embryonic development. Like other members of the bone morphogenetic protein family, BMP-7 works synergistically with BMP-2 to play a key role in the differentiation of mesenchymal cells into bone and cartilage tissues by actively recruiting stem cells from the surrounding tissue, thereby initiating the bone formation cascade. In adult cells, BMP-7 is predominately expressed in the brain, kidneys, and bladder.
Application
Immunohistochemistry: Recommended working dilution is 1:50.
Western Blotting: Recommended working concentration is 1 – 2 µg/mL.
Western Blotting: Recommended working concentration is 1 – 2 µg/mL.
This Anti-BMP-7 Antibody, clone 2A10 is validated for use in WB, IH for the detection of BMP-7.
Biochem/physiol Actions
Reactivity with other species has not been tested.
Physical form
Format: Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4),
150 mM NaCl, and 0.05% sodium azide.
150 mM NaCl, and 0.05% sodium azide.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Oral administration of recombinant adeno-associated virus-mediated bone morphogenetic protein-7 suppresses CCl(4)-induced hepatic fibrosis in mice.
Hao, ZM; Cai, M; Lv, YF; Huang, YH; Li, HH
Molecular Therapy null
Rongrong Zhang et al.
Communications biology, 7(1), 266-266 (2024-03-05)
Long noncoding RNA small nucleolar RNA host gene 5 (SNHG5) is an oncogene found in various human cancers. However, it is unclear what role SNHG5 plays in activating hepatic stellate cells (HSCs) and liver fibrosis. In this study, SNHG5 was
Ariadne Cristiane Cabral Cruz et al.
Journal of applied oral science : revista FOB, 20(6), 628-635 (2013-01-19)
Bone morphogenetic protein type 2 (BMP-2) is a potent local factor, which promotes bone formation and has been used as an osteogenic supplement for mesenchymal stem cells. This study evaluated the effect of a recombinant BMP-2 as well as the
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB4350 | 04053252505072 |