MAB5596
Anti-HCN2 Antibody
culture supernatant, Chemicon®
Synonym(s):
Hyperpolarization-activated and cyclic nucleotide-gated channel 2
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
monoclonal
Application:
IHC, WB
Citations:
3
biological source
rat
Quality Level
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
monoclonal
species reactivity
mouse, rat
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
mouse ... Hcn2(15166)
rat ... Hcn2(114244)
Immunogen
Synthetic peptide from rat HCN2.
Application
Anti-HCN2 Antibody is an antibody against HCN2 for use in IH & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Ion Channels & Transporters
Ion Channels & Transporters
Western blot on rat and mouse retina. The antibody recognizes a weak band at ~98 kDa and a stronger band at ~108 kDa in glycosylated protein from a retinal membrane preparation.
Immunohistochemistry on rat and mouse retina.
Optimal working dilutions must be determined by end user.
Immunohistochemistry on rat and mouse retina.
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
HCN2 (Hyperpolarization-activated and cyclic nucleotide-gated channel 2). The antibody recognizes both the glycosyated and deglycosylated form of HCN2. The antibody recognizes a weak band at ~98 kDa and a stronger band at ~108 kDa in glycosylated protein from a retinal membrane preparation.
Physical form
Cultured supernatant containing 0.05% sodium azide.
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Joon Ha Park et al.
International journal of molecular medicine, 44(5), 1801-1810 (2019-10-02)
Hyperpolarization‑activated cyclic nucleotide‑gated (HCN) channels have been known to participate in the regulation of neuronal excitability, synaptic transmission and long‑term potentiation in the hippocampus. The present study investigated transient ischemia‑induced changes of HCN1 and HCN2 expressions in the Cornu Ammonis
Stuart M Cain et al.
Pflugers Archiv : European journal of physiology, 467(6), 1367-1382 (2014-06-24)
Burst-firing in distinct subsets of thalamic relay (TR) neurons is thought to be a key requirement for the propagation of absence seizures. However, in the well-regarded Genetic Absence Epilepsy Rats from Strasbourg (GAERS) model as yet there has been no
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB5596 | 04053252398230 |