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Merck
CN

MAB8905

Anti-Measles Blend Antibody, hemagglutinin, clones CV1, CV4

ascites fluid, Chemicon®, from mouse

Synonym(s):

Rubeola

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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Product Name

Anti-Measles Blend Antibody, hemagglutinin, clones CV1, CV4, ascites fluid, Chemicon®, from mouse

biological source

mouse

antibody form

ascites fluid

clone

CV1, monoclonal
CV4, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)

isotype

IgG1

shipped in

wet ice

Quality Level

Application

Indirect immunofluorescence at 1:100-1:1,000 using acetone fixation.

Immunohistochemistry on paraffin embedded sections (Grote et al., 2001).



Final working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
This Anti-Measles Blend Antibody, hemagglutinin, clones CV1, CV4 is validated for use in IF, IH(P) for the detection of Measles Blend.

Biochem/physiol Actions

A blend of two monoclonal antibodies that recognize the measles hemagglutinin protein by indirect immunofluorescence.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Epitope: hemagglutinin
Hemagglutinin protein obtained from Chicago wild type strain of measles

Physical form

Liquid ascites fluid containing no preservatives.

Preparation Note

Maintain at -20°C in convenient aliquots for up to 12 months.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Luminita Ene et al.
Frontiers in cellular neuroscience, 17, 1113935-1113935 (2023-04-21)
An unusual cluster of myoclonic epilepsy was observed in a Romanian pediatric HIV cohort concurrent with measles outbreaks. We describe this particular form of subacute measles encephalitis (SME) in a group of HIV-infected children and adolescents with severe immunosuppression. This
Michael N Ha et al.
Journal of virology, 91(23) (2017-09-15)
The inhibitors carbobenzoxy (Z)-d-Phe-l-Phe-Gly (fusion inhibitor peptide [FIP]) and 4-nitro-2-phenylacetyl amino-benzamide (AS-48) have similar efficacies in blocking membrane fusion and syncytium formation mediated by measles virus (MeV). Other homologues, such as Z-d-Phe, are less effective but may act through the
Live attenuated measles virus induces regression of human lymphoma xenografts in immunodeficient mice.
Grote, D, et al.
Blood, 97, 3746-3754 (2001)
Measles virus selectively blind to signaling lymphocytic activation molecule (SLAM; CD150) is attenuated and induces strong adaptive immune responses in rhesus monkeys.
VH Leonard, G Hodge, J Reyes-Del Valle, MB McChesney, R Cattaneo
Journal of virology null
The measles virus fusion protein transmembrane region modulates availability of an active glycoprotein complex and fusion efficiency.
Muhlebach, MD; Leonard, VH; Cattaneo, R
Journal of virology null

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