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Merck
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MABC82

Anti-RIP1/RIPK1 Antibody, clone 3C6.1

clone 3C6.1, from mouse

Synonym(s):

Receptor-interacting serine/threonine-protein kinase 1, Cell death protein RIP, Receptor-interacting protein 1, RIP-1, Serine/threonine-protein kinase RIP

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
3C6.1, monoclonal
Application:
WB
Citations:
-

Key Documents

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biological source

mouse

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

3C6.1, monoclonal

species reactivity

human

technique(s)

western blot: suitable

isotype

IgG2aκ

NCBI accession no.

NP_003795

UniProt accession no.

Q13546

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... RIPK1(8737)

General description

~ 76 kDa observed
Receptor-interacting serine/threonine-protein kinase 1, also known as Cell death protein RIP or Receptor-interacting protein 1 (RIP-1) or Serine/threonine-protein kinase RIP, and encoded by the gene name RIPK1 or RIP or RIP1, contains 1 death domain and 1 protein kinase domain. RIPK1 is localized to the cytoplasm and plays an important role in a variety of cellular pathways including the NF-κB pathway and programmed necrotic cell death (necroptosis).

Immunogen

GST-tagged recombinant protein corresponding to human RIP1/RIPK1.

Application

Detect RIP1/RIPK1 using this Anti-RIP1/RIPK1 Antibody, clone 3C6.1 validated for use in western blotting.

Physical form

Format: Purified

Analysis Note

Evaluated by Western Blotting in Jurkat cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected RIP1/RIPK1 in 200 µg of Jurkat cell lysate.

Other Notes

Replaces: MABC688
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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