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Merck
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MABE450

Anti-TAF15, clone 8TA-2B10 Antibody

ascites fluid, clone 8TA-2B10, from mouse

Synonym(s):

TATA-binding protein-associated factor 2N, 68 kDa TATA-binding protein-associated factor, TAF(II)68, TAFII68, RNA-binding protein 56

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
8TA-2B10, monoclonal
Application:
immunoprecipitation (IP)
western blot
Species reactivity:
rat, mouse, human
Citations:
1
Technique(s):
immunoprecipitation (IP): suitable
western blot: suitable
Uniprot accession no.:
Q92804

Key Documents

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Product Name

Anti-TAF15, clone 8TA-2B10 Antibody, ascites fluid, clone 8TA-2B10, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

8TA-2B10, monoclonal

species reactivity

rat, mouse, human

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1κ

NCBI accession no.

NP_003478

UniProt accession no.

Q92804

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... TAF15(8148)

Analysis Note

Evaluated by Western Blotting in A431 cell lysate.

Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected TAF15 in 10 µg of A431 cell lysate.

Application

Anti-TAF15 antibody, clone 8TA-2B10 is an antibody against TAF15 for use in western blotting & IP.

General description

TAF15, also known as TATA-binding protein-associated factor 2N, or 68 kDa TATA-binding protein-associated factor, or TAF(II)68, TAFII68, or RNA-binding protein 56, and encoded by the gene TAF15/RBP56/TAF2N, is a RNA and ssDNA binding protein important in transcription initiation. TAF15 aligns with the RNA polymerase II (Pol II) multiprotein complex that together with other proteins like TBP initiates transcription. TAF15 is ubiquitously expressed, and TAF15 shuttles from the nucleus to the cytoplasm upon activation; methylation of TAF15 appears to guide nuclear localization and transcriptional activity. Translocations involving the TAF15 gene may play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene are associated with amyotrophic lateral sclerosis (ALS) diseases.
~68 kDa observed

Physical form

Mouse monoclonal IgG1κ ascites without preservatives.

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yan Wang et al.
Oncotarget, 8(67), 111866-111881 (2018-01-18)
S-adenosyl methionine (SAM) is a ubiquitous methyl donor that was reported to have chemo- protective activity against liver cancer, however the molecular footprint of SAM is unknown. We show here that SAM selectively inhibits growth, transformation and invasiveness of hepatocellular

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