MABN2522
Anti-α-Synuclein (SNCA) Antibody
mouse monoclonal, Syn506
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Product Name
Anti-alpha-synuclein Antibody, clone Syn506,
antibody form
purified antibody
clone
Syn506
monoclonal
purified by
using protein G
species reactivity
human, mouse, mouse
concentration
(Please refer to lot specific datasheet.)
technique(s)
ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
isotype
IgG1κ
UniProt accession no.
General description
14.46 kDa calculated
Recombinant human alpha-synuclein oxidized/nitrated in vitro with peroxynitrite.
Application
ELISA Analysis: A representative lot detected alpha synuclein in ELISA applications (Waxman, E.A., et. al. (2008). Acta Neuropathol. 116(1):37-46).
Immunohistochemistry (Paraffin) Analysis: A representative lot detected alpha synuclein in Immunohistochemistry applications (Waxman, E.A., et. al. (2008). Acta Neuropathol. 116(1):37-46; Sorrentino, Z.A., et. al. (2017). Mol Neurodegener. 12(1):40; Peng, C., et. al. (2018). Nature. 557(7706):558-563).
Western Blotting Analysis: A representative lot detected alpha synuclein in Western Blotting applications (Waxman, E.A., et. al. (2008). Acta Neuropathol. 116(1):37-46).
Immunocytochemistry Analysis: A representative lot detected alpha synuclein in Immunocytochemistry applications (Waxman, E.A., et. al. (2008). Acta Neuropathol. 116(1):37-46).
Immunohistochemistry (Paraffin) Analysis: A representative lot detected alpha synuclein in Immunohistochemistry applications (Waxman, E.A., et. al. (2008). Acta Neuropathol. 116(1):37-46; Sorrentino, Z.A., et. al. (2017). Mol Neurodegener. 12(1):40; Peng, C., et. al. (2018). Nature. 557(7706):558-563).
Western Blotting Analysis: A representative lot detected alpha synuclein in Western Blotting applications (Waxman, E.A., et. al. (2008). Acta Neuropathol. 116(1):37-46).
Immunocytochemistry Analysis: A representative lot detected alpha synuclein in Immunocytochemistry applications (Waxman, E.A., et. al. (2008). Acta Neuropathol. 116(1):37-46).
Biochem/physiol Actions
Clone Syn506 is a mouse monoclonal antibody that detects misfolded alpha-synuclein. It targets an epitope within 20 amino acids from the N-terminal region.
Physical form
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Evaluated by Immunohistochemistry (Paraffin) in human Parkinson′s diseased brain tissue sections.
Immunohistochemistry (Paraffin) Analysis: A 1:250 dilution of this antibody detected alpha synuclein in human Parkinson′s diseased brain tissue sections.
Immunohistochemistry (Paraffin) Analysis: A 1:250 dilution of this antibody detected alpha synuclein in human Parkinson′s diseased brain tissue sections.
Other Notes
Human, Mouse.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Regulatory Information
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