Anti-Neuroligin-1, clone 1C9.1 Antibody

Neuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses for their normal, functional development, and is necessary to the regulation of synaptic plasticity and the development of long-term memory within the adult amygdala in mammals. It is believed to participate in cell-cell-interaction through the assembly of intracellular junction by the binding of beta-neurexins, and may also be a factor in the maintenance and assembly of synaptic junctions. It is also thought to have involvement in excitatory synaptic specification. Within brain tissue, Neuroligin-1 is primarily observed in neurons and spinal cord.

~94 kDa observed

Epitope: Extracellular domain

GST-tagged recombinant protein corresponding to the extracellular domain of Human Neuroligin-1.

This Anti-Neuroligin-1, clone 1C9.1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of Neuroligin-1.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Neuroligin-1 in human cerebral cortex, rat cerebellum and rat cerebral cortex tissue.

Research Category
Neuroscience

Neuroscience

Research Sub Category
Synapse & Synaptic Biology

Growth Cones & Axon Guidance

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Evaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Neuroligin-1 in 10 µg of rat brain tissue lysate.

Concentration: Please refer to lot specific datasheet.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.