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Merck
CN

MABT478

Sigma-Aldrich

Anti-BCAR3 Antibody, clone 9D9.1

clone 9D9.1, from mouse

Synonym(s):

Breast cancer anti-estrogen resistance protein 3, Novel SH2-containing protein 2, SH2 domain-containing protein 3B

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Key Documents

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biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

9D9.1, monoclonal

species reactivity

human

technique(s)

western blot: suitable

isotype

IgG1κ

NCBI accession no.

NP_001248337

UniProt accession no.

O75815

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... BCAR3(8412)

General description

Breast cancer anti-estrogen resistance protein 3 (BCAR3), also known as Novel SH2-containing protein 2 (NSP2) and SH2 domain-containing protein 3B (SH2D3B) is an adapter protein that regulates the proliferation in breast cancer cells. BCAR3 may also be regulated by cellular adhesion to extracellular matrix proteins. BCAR3 is found in several cancer cell lines; however, it is not found in nonmalignant breast tissue. When BCAR3 is overexpressed, it confers anti-estrogen resistance in breast cancer cell lines.
~93 kDa observed

Immunogen

GST-tagged recombinant protein corresponding to human BCAR3.

Application

Anti-BCAR3, clone 9D9.1 is an antibody against BCAR3 for use in Western Blotting.
Research Category
Cell Structure
Research Sub Category
Adhesion (CAMs)

Physical form

Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in U2OS cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected BCAR3 in 10 µg of U2OS cell lysate.

Other Notes

Concentration: Please refer to lot specific datasheet.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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