MADKMAG-71K
MILLIPLEX® Mouse Adipokine Panel
Configurable Mouse Adipokine 7-Plex Panel
Synonym(s):
luminex mouse adipokine multiplex kit, luminex mouse obesity multiplex kit, millipore mouse metabolic syndrome disease multiplex, mouse metabolism diabetes immunoassay panel
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About This Item
UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000
species reactivity
mouse
Quality Level
packaging
pkg of 1 ea
manufacturer/tradename
Milliplex®
assay range
accuracy: 77-92%, standard curve range: 12.2-50,000 pg/mL
technique(s)
multiplexing: suitable
input
serum
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
General description
Adipokines such as insulin, leptin, resistin, adiponectin, IL-6, TNF-α, MCP-1, and PAI-1 are key regulators of energy metabolism, inflammation, and endocrine signaling. Insulin facilitates glucose uptake, leptin controls appetite and energy balance, and resistin is linked to insulin resistance. Adiponectin enhances insulin sensitivity, while IL-6 and TNF-α are central to obesity-related inflammation. MCP-1 recruits immune cells to adipose tissue, and PAI-1 influences fibrinolysis and metabolic dysfunction. Together, these biomarkers offer a comprehensive view of adipose tissue function and its systemic impact on metabolic health.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 7 analytes in mouse serum or plasma samples.
Analytes included: Insulin, Leptin, Resistin, Adiponectin, IL-6, TNF-α, MCP-1, PAI-1 (Total)
Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy
Analytes included: Insulin, Leptin, Resistin, Adiponectin, IL-6, TNF-α, MCP-1, PAI-1 (Total)
Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy
Features and Benefits
Features:
- Measures key adipokines and cytokines involved in metabolic regulation and inflammation
- Includes analytes such as insulin, leptin, resistin, adiponectin, IL-6, TNF-α, MCP-1, and PAI-1 (Total)
- Enables multiplex detection for efficient and simultaneous analysis
- Compatible with mouse serum, plasma, and tissue culture supernatant samples
- Designed for use in metabolic, obesity, and inflammation-related research
- Provides a comprehensive profile of adipose tissue function and systemic metabolic health
- Supports early identification of insulin resistance, obesity-related inflammation, and metabolic dysfunction
- Facilitates evaluation of therapeutic interventions targeting adipokine pathways
- Enhances understanding of endocrine and immune interactions in preclinical models
- Streamlines experimental workflows with high-throughput, multi-analyte capability
Legal Information
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1
Storage Class
10 - Combustible liquids
wgk
WGK 3
Regulatory Information
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Salman Azhar et al.
Molecular and cellular endocrinology, 480, 1-11 (2018-10-06)
Previously, apoE-derived ABCA1 agonist peptides have been shown to possess anti-atherosclerotic and possibly antidiabetic properties. Here we assessed the in vitro and in vivo actions of a second generation of ABCA1 peptide agonists, CS6253 and T6991-2, on glucose homeostasis. The
Dimiter Avtanski et al.
Animal models and experimental medicine, 2(4), 252-258 (2020-01-17)
Animal models of diet-induced obesity (DIO) are commonly used in medical research for mimicking human diseases. There is no universal animal model, and careful evaluation of variety of factors needs to be considered when designing new experiments. Here, we investigated
Brandon D Kayser et al.
PloS one, 10(3), e0121954-e0121954 (2015-04-04)
Obesity causes white adipose tissue (WAT) inflammation and insulin resistance in some, but not all individuals. Here, we used a mouse model of early postnatal overfeeding to determine the role of neonatal nutrition in lifelong WAT inflammation and metabolic dysfunction.
Sara A DiVall et al.
PloS one, 10(3), e0119995-e0119995 (2015-03-18)
Infertility associated with obesity is characterized by abnormal hormone release from reproductive tissues in the hypothalamus, pituitary, and ovary. These tissues maintain insulin sensitivity upon peripheral insulin resistance. Insulin receptor signaling may play a role in the dysregulation of gonadotropin-releasing
Linda A Toth et al.
Journal of the American Association for Laboratory Animal Science : JAALAS, 54(6), 708-717 (2015-12-04)
To determine how housing density and ambient temperature interact to influence the physiology and behavior of mice, we systematically varied housing density (1 to 5 mice per cage) and ambient temperature (22, 26, or 30 °C) and measured effects on
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Multiplex immunoassays, such as MILLIPLEX® multiplex metabolic assays, are critical in metabolic syndrome research because they provide a full picture of the different conditions related to it, like diabetes and obesity, as well as save time and sample volume.
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