MILLIPLEX^® Mouse Aging Panel 1

Biomarkers such as CTACK/CCL27, FGF-21, GnRH, IL-6, Jag1, Leptin, Notch1, and TNFα are central to understanding the biological processes of aging in mouse models. CTACK/CCL27 is involved in skin-associated immune signaling, while FGF-21 regulates metabolic adaptation and longevity. GnRH controls reproductive aging, and IL-6 and TNFα are key inflammatory cytokines linked to age-related immune dysregulation. Jag1 and Notch1 are part of the Notch signaling pathway, which influences cellular differentiation and tissue regeneration. Leptin reflects changes in energy balance and adipose tissue function. Together, these analytes provide a comprehensive view of molecular aging and systemic decline.

For optimal sensitivity, use an overnight (16-18 hour) incubation. Serum and plasma samples require (recommend) a 1:2 dilution with Assay Buffer. Tissue culture supernatants may be run neat or appropriately diluted in control medium. Each well requires 25 μL of sample, standard or control.Analytes available:CTACK/CCL27, FGF-21, GnRH, IL-6, Jag1, Leptin, Notch1, TNFα.

Design your multiplex kit by choosing available analytes within this panel.

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For research use only. Not for use in diagnostic procedures.

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