MCKP1-110K
MILLIPLEX® Mouse Immuno-Oncology Checkpoint Protein Panel 1
Configurable Mouse Immuno-Oncology Checkpoint Protein 28-Plex Panel 1
Synonym(s):
luminex mouse immuno oncology checkpoint protein multiplex kit, millipore mouse IO checkpoint protein multiplex, mouse I O cancer immunoassay panel
Product Name
MILLIPLEX® Mouse Immuno-Oncology Checkpoint Protein Panel 1, Configurable Mouse Immuno-Oncology Checkpoint Protein 28-Plex Panel 1
species reactivity
mouse
manufacturer/tradename
Milliplex®
Quality Level
packaging
1 ea of
assay range
accuracy: 101
(Galectin-1)
accuracy: 103
(CD80/B7-1)
accuracy: 103
(IFNγ)
accuracy: 104
(CTLA-4/CD152)
accuracy: 104
(PD-L2)
accuracy: 104
(TLR-2)
accuracy: 105
(4-1BBL/TNFSF9)
accuracy: 105
(BCA-1/CXCL-13)
accuracy: 105
(CD25/IL-2Rα)
accuracy: 105
(IL-10)
accuracy: 105
(LAG-3)
accuracy: 106
(5’-NT/CD73)
accuracy: 106
(PD-1)
accuracy: 106
(TIM-3)
accuracy: 106
(TNFα)
accuracy: 107
(CD137/4-1BB)
accuracy: 107
(CD27)
accuracy: 108
(E-Cadherin)
accuracy: 108
(Galectin-3)
accuracy: 108
(HVEM)
accuracy: 109
(CD40)
accuracy: 109
(GITR)
accuracy: 110
(B7-H2/ICOSL)
accuracy: 110
(CD226/DNAM-1)
accuracy: 111
(BTLA)
accuracy: 94
(GranzymeB)
accuracy: 95
(B7-H3/CD276)
accuracy: 96
(PD-L1)
standard curve range: 1.4 - 1000 pg/mL
(HVEM)
standard curve range: 11 - 8000 pg/mL
(IL-10)
standard curve range: 137-100,000 pg/mL
(5’-NT/CD73)
standard curve range: 14 - 10000 pg/mL
(CD226/DNAM-1)
standard curve range: 14 - 10000 pg/mL
(CD40)
standard curve range: 14 - 10000 pg/mL
(PD-L1)
standard curve range: 14-10,000 pg/mL
(4-1BBL/TNFSF9)
standard curve range: 2.1 - 1500 pg/mL
(IFNγ)
standard curve range: 2.7 - 2000 pg/mL
(CD25/IL-2Rα)
standard curve range: 21-15000 pg/mL
(BTLA)
standard curve range: 27-20000 pg/mL
(B7-H2/ICOSL)
standard curve range: 27-20000 pg/mL
(BCA-1/CXCL-13)
standard curve range: 3.4 - 2500 ng/mL
(Galectin-1)
standard curve range: 3.4-2500 ng/mL
(B7-H3/CD276)
standard curve range: 34.3 - 25000 pg/mL
(CD80/B7-1)
standard curve range: 342 - 250000 pg/mL
(E-Cadherin)
standard curve range: 4.1 - 3000 pg/mL
(TNFα)
standard curve range: 41 - 30000 pg/mL
(GITR)
standard curve range: 41 - 30000 pg/mL
(Galectin-3)
standard curve range: 412 - 300000 pg/mL
(LAG-3)
standard curve range: 412 - 300000 pg/mL
(TLR-2)
standard curve range: 5.5 - 4000 pg/mL
(CD137/4-1BB)
standard curve range: 5.5 - 4000 pg/mL
(CTLA-4/CD152)
standard curve range: 5.5 - 4000 pg/mL
(TIM-3)
standard curve range: 55 - 40000 pg/mL
(CD27)
standard curve range: 55 - 40000 pg/mL
(PD-1)
standard curve range: 6.9 - 5000 pg/mL
(PD-L2)
standard curve range: 8.2 - 6000 pg/mL
(GranzymeB)
technique(s)
multiplexing: suitable
input
cell lysate
cell culture supernatant
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
Legal Information
Application
Analytes included: 4-1BBL/TNFSF9, 5′-NT/CD73, B7-H2/ICOSL, B7-H3/CD276, BCA-1/CXCL-13, BTLA, CD137/4-1BB, CD226/DNAM-1, CD25/IL-2Rα, CD27, CD40, CD80/B7-1, CTLA-4/CD152, E-cadherin, Galectin-1, Galectin-3, GITR, Granzyme B, HVEM, IFNγ, IL-10, LAG-3, PD-1, PD-L1, PD-L2, TIM-3, TLR-2, and TNFα
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Disclaimer
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Features and Benefits
Accelerates Immuno-Oncology Research: Enables detailed profiling of immune checkpoint dynamics in tumor microenvironments and circulation and supports studies on immune escape mechanisms and response to immunotherapies.
Supports Biomarker Discovery: Facilitates identification of soluble checkpoint proteins as potential biomarkers for cancer and immunological diseases.
Verified Performance: Offers lot-to-lot consistency and analytical validation, critical for reproducible results in research.
Flexible Applications: Suitable for basic research, preclinical studies, and drug development involving mouse models.
General description
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
target_organs
Respiratory Tract
Storage Class
10 - Combustible liquids
wgk
WGK 3
Regulatory Information
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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