MCKP1-110K
MILLIPLEX® Mouse Immuno-Oncology Checkpoint Protein Panel 1
Configurable Mouse Immuno-Oncology Checkpoint Protein 28-Plex Panel 1
Synonym(s):
Luminex mouse immuno oncology panel, checkpoint inhibitor multiplex assay, mouse IO panel, mouse cancer immunotherapy assay, mouse immune checkpoint profiling kit
About This Item
Product Name
MILLIPLEX® Mouse Immuno-Oncology Checkpoint Protein Panel 1,
description
Configurable Mouse Immuno-Oncology Checkpoint Protein 28-Plex Panel 1
Quality Level
species reactivity
mouse
packaging
pkg of 1 ea
manufacturer/tradename
Milliplex®
assay range
standard curve range: 14-10,000 pg/mL
(4-1BBL/TNFSF9), standard curve range: 2.1 - 1500 pg/mL
(IFNγ), standard curve range: 2.7 - 2000 pg/mL
(CD25/IL-2Rα), standard curve range: 21-15000 pg/mL
(BTLA), standard curve range: 27-20000 pg/mL
(B7-H2/ICOSL), standard curve range: 27-20000 pg/mL
(BCA-1/CXCL-13), standard curve range: 3.4 - 2500 ng/mL
(Galectin-1), standard curve range: 3.4-2500 ng/mL
(B7-H3/CD276), standard curve range: 34.3 - 25000 pg/mL
(CD80/B7-1), standard curve range: 342 - 250000 pg/mL
(E-Cadherin), standard curve range: 4.1 - 3000 pg/mL
(TNFα), standard curve range: 41 - 30000 pg/mL
(GITR), standard curve range: 41 - 30000 pg/mL
(Galectin-3), standard curve range: 412 - 300000 pg/mL
(LAG-3), standard curve range: 412 - 300000 pg/mL
(TLR-2), standard curve range: 5.5 - 4000 pg/mL
(CD137/4-1BB), standard curve range: 5.5 - 4000 pg/mL
(CTLA-4/CD152), standard curve range: 5.5 - 4000 pg/mL
(TIM-3), standard curve range: 55 - 40000 pg/mL
(CD27), standard curve range: 55 - 40000 pg/mL
(PD-1), standard curve range: 6.9 - 5000 pg/mL
(PD-L2), standard curve range: 8.2 - 6000 pg/mL
(GranzymeB), accuracy: 101
(Galectin-1), accuracy: 103
(CD80/B7-1), accuracy: 103
(IFNγ), accuracy: 104
(CTLA-4/CD152), accuracy: 104
(PD-L2), accuracy: 104
(TLR-2), accuracy: 105
(4-1BBL/TNFSF9), accuracy: 105
(BCA-1/CXCL-13), accuracy: 105
(CD25/IL-2Rα), accuracy: 105
(IL-10), accuracy: 105
(LAG-3), accuracy: 106
(5’-NT/CD73), accuracy: 106
(PD-1), accuracy: 106
(TIM-3), accuracy: 106
(TNFα), accuracy: 107
(CD137/4-1BB), accuracy: 107
(CD27), accuracy: 108
(E-Cadherin), accuracy: 108
(Galectin-3), accuracy: 108
(HVEM), accuracy: 109
(CD40), accuracy: 109
(GITR), accuracy: 110
(B7-H2/ICOSL), accuracy: 110
(CD226/DNAM-1), accuracy: 111
(BTLA), accuracy: 94
(GranzymeB), accuracy: 95
(B7-H3/CD276), accuracy: 96
(PD-L1), standard curve range: 1.4 - 1000 pg/mL
(HVEM), standard curve range: 11 - 8000 pg/mL
(IL-10), standard curve range: 137-100,000 pg/mL
(5’-NT/CD73), standard curve range: 14 - 10000 pg/mL
(CD226/DNAM-1), standard curve range: 14 - 10000 pg/mL
(CD40), standard curve range: 14 - 10000 pg/mL
(PD-L1)
technique(s)
multiplexing: suitable
input
cell culture supernatant(s)
serum
plasma
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
General description
Application
Analytes included: 4-1BBL/TNFSF9, 5′-NT/CD73, B7-H2/ICOSL, B7-H3/CD276, BCA-1/CXCL-13, BTLA, CD137/4-1BB, CD226/DNAM-1, CD25/IL-2Rα, CD27, CD40, CD80/B7-1, CTLA-4/CD152, E-cadherin, Galectin-1, Galectin-3, GITR, Granzyme B, HVEM, IFNγ, IL-10, LAG-3, PD-1, PD-L1, PD-L2, TIM-3, TLR-2, and TNFα
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
Accelerates Immuno-Oncology Research: Enables detailed profiling of immune checkpoint dynamics in tumor microenvironments and circulation and supports studies on immune escape mechanisms and response to immunotherapies.
Supports Biomarker Discovery: Facilitates identification of soluble checkpoint proteins as potential biomarkers for cancer and immunological diseases.
Verified Performance: Offers lot-to-lot consistency and analytical validation, critical for reproducible results in research.
Flexible Applications: Suitable for basic research, preclinical studies, and drug development involving mouse models.
Legal Information
Disclaimer
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
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Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
target_organs
Respiratory Tract
Storage Class
10 - Combustible liquids
wgk
WGK 3
Regulatory Information
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Certificates of Analysis (COA)
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