MCKP1-110K
MILLIPLEX® Mouse Immuno-Oncology Checkpoint Protein Panel 1
Configurable Mouse Immuno-Oncology Checkpoint Protein 28-Plex Panel 1
Synonym(s):
Luminex mouse immuno oncology panel, checkpoint inhibitor multiplex assay, mouse IO panel, mouse cancer immunotherapy assay, mouse immune checkpoint profiling kit
species reactivity
mouse
Quality Level
packaging
pkg of 1 ea
manufacturer/tradename
Milliplex®
assay range
accuracy: 101
(Galectin-1), accuracy: 103
(CD80/B7-1), accuracy: 103
(IFNγ), accuracy: 104
(CTLA-4/CD152), accuracy: 104
(PD-L2), accuracy: 104
(TLR-2), accuracy: 105
(4-1BBL/TNFSF9), accuracy: 105
(BCA-1/CXCL-13), accuracy: 105
(CD25/IL-2Rα), accuracy: 105
(IL-10), accuracy: 105
(LAG-3), accuracy: 106
(5’-NT/CD73), accuracy: 106
(PD-1), accuracy: 106
(TIM-3), accuracy: 106
(TNFα), accuracy: 107
(CD137/4-1BB), accuracy: 107
(CD27), accuracy: 108
(E-Cadherin), accuracy: 108
(Galectin-3), accuracy: 108
(HVEM), accuracy: 109
(CD40), accuracy: 109
(GITR), accuracy: 110
(B7-H2/ICOSL), accuracy: 110
(CD226/DNAM-1), accuracy: 111
(BTLA), accuracy: 94
(GranzymeB), accuracy: 95
(B7-H3/CD276), accuracy: 96
(PD-L1), standard curve range: 1.4 - 1000 pg/mL
(HVEM), standard curve range: 11 - 8000 pg/mL
(IL-10), standard curve range: 137-100,000 pg/mL
(5’-NT/CD73), standard curve range: 14 - 10000 pg/mL
(CD226/DNAM-1), standard curve range: 14 - 10000 pg/mL
(CD40), standard curve range: 14 - 10000 pg/mL
(PD-L1), standard curve range: 2.1 - 1500 pg/mL
(IFNγ), standard curve range: 2.7 - 2000 pg/mL
(CD25/IL-2Rα), standard curve range: 21-15000 pg/mL
(BTLA), standard curve range: 27-20000 pg/mL
(B7-H2/ICOSL), standard curve range: 27-20000 pg/mL
(BCA-1/CXCL-13), standard curve range: 3.4 - 2500 ng/mL
(Galectin-1), standard curve range: 3.4-2500 ng/mL
(B7-H3/CD276), standard curve range: 34.3 - 25000 pg/mL
(CD80/B7-1), standard curve range: 342 - 250000 pg/mL
(E-Cadherin), standard curve range: 4.1 - 3000 pg/mL
(TNFα), standard curve range: 41 - 30000 pg/mL
(GITR), standard curve range: 41 - 30000 pg/mL
(Galectin-3), standard curve range: 412 - 300000 pg/mL
(LAG-3), standard curve range: 412 - 300000 pg/mL
(TLR-2), standard curve range: 5.5 - 4000 pg/mL
(CD137/4-1BB), standard curve range: 5.5 - 4000 pg/mL
(CTLA-4/CD152), standard curve range: 5.5 - 4000 pg/mL
(TIM-3), standard curve range: 55 - 40000 pg/mL
(CD27), standard curve range: 55 - 40000 pg/mL
(PD-1), standard curve range: 6.9 - 5000 pg/mL
(PD-L2), standard curve range: 8.2 - 6000 pg/mL
(GranzymeB)
technique(s)
multiplexing: suitable
input
cell lysate
cell culture supernatant
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
Looking for similar products? Visit Product Comparison Guide
General description
Application
Analytes included: 4-1BBL/TNFSF9, 5′-NT/CD73, B7-H2/ICOSL, B7-H3/CD276, BCA-1/CXCL-13, BTLA, CD137/4-1BB, CD226/DNAM-1, CD25/IL-2Rα, CD27, CD40, CD80/B7-1, CTLA-4/CD152, E-cadherin, Galectin-1, Galectin-3, GITR, Granzyme B, HVEM, IFNγ, IL-10, LAG-3, PD-1, PD-L1, PD-L2, TIM-3, TLR-2, and TNFα
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
Accelerates Immuno-Oncology Research: Enables detailed profiling of immune checkpoint dynamics in tumor microenvironments and circulation and supports studies on immune escape mechanisms and response to immunotherapies.
Supports Biomarker Discovery: Facilitates identification of soluble checkpoint proteins as potential biomarkers for cancer and immunological diseases.
Verified Performance: Offers lot-to-lot consistency and analytical validation, critical for reproducible results in research.
Flexible Applications: Suitable for basic research, preclinical studies, and drug development involving mouse models.
Legal Information
Disclaimer
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
target_organs
Respiratory Tract
Storage Class
10 - Combustible liquids
wgk
WGK 3
Regulatory Information
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Related Content
Discover the benefits of MILLIPLEX® multiplex assays, based on Luminex® xMAP® multiplex assay technology, that provide consistent, high-quality results and see how these multiplex biomarker Luminex® assays are being used to advance research.
Research evaluating immune checkpoints may help identify those likely to benefit from PD-1/PD-L1 immunotherapy and reveal new immunotherapy targets for future investigation. See how the MILLIPLEX® Human Immuno-Oncology Checkpoint Protein Panel 2 was used to multiplex immune checkpoint molecules for NSCLC research.
Get even more out of your samples with this Luminex® technology-based mouse cytokine assay – the MILLIPLEX® Mouse Cytokine Expanded Panel 1.
评估免疫检查点有助于明确在PD-1/PD-L1免疫疗法中获益的患者，并为后续研究揭示新的免疫治疗靶点。了解如何使用MILLIPLEX® Human Immuno-Oncology Checkpoint Protein Panel 2进行免疫检查点分子的多重检测评估来研究NSCLC疗法。
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service