MCKP1-110K-PX28
MILLIPLEX® Mouse Immuno-Oncology Checkpoint Protein Panel 1
Premixed Mouse Immuno-Oncology Checkpoint Protein 28-Plex Panel 1
Synonym(s):
Luminex mouse immuno oncology panel, checkpoint inhibitor multiplex assay, mouse IO panel, mouse cancer immunotherapy assay, mouse immune checkpoint profiling kit
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About This Item
Product Name
MILLIPLEX® Mouse Immuno-Oncology Checkpoint Protein Panel 1,
species reactivity
mouse
Quality Level
description
Premixed Mouse Immuno-Oncology Checkpoint Protein 28-Plex Panel 1
packaging
pkg of 1 ea
manufacturer/tradename
Milliplex®
assay range
inter-assay cv: <20%
intra-assay cv: <10%, accuracy: 101
(Galectin-1), accuracy: 103
(CD80/B7-1), accuracy: 103
(IFNγ), accuracy: 104
(CTLA-4/CD152), accuracy: 104
(PD-L2), accuracy: 104
(TLR-2), accuracy: 105
(4-1BBL/TNFSF9), accuracy: 105
(BCA-1/CXCL-13), accuracy: 105
(CD25/IL-2Rα), accuracy: 105
(IL-10), accuracy: 105
(LAG-3), accuracy: 106
(5’-NT/CD73), accuracy: 106
(PD-1), accuracy: 106
(TIM-3), accuracy: 106
(TNFα), accuracy: 107
(CD137/4-1BB), accuracy: 107
(CD27), accuracy: 108
(E-Cadherin), accuracy: 108
(Galectin-3), accuracy: 108
(HVEM), accuracy: 109
(CD40), accuracy: 109
(GITR), accuracy: 110
(B7-H2/ICOSL), accuracy: 110
(CD226/DNAM-1), accuracy: 111
(BTLA), accuracy: 94
(GranzymeB), accuracy: 95
(B7-H3/CD276), accuracy: 96
(PD-L1), standard curve range: 1.4 - 1000 pg/mL
(HVEM), standard curve range: 11 - 8000 pg/mL
(IL-10), standard curve range: 137 - 100000 pg/mL
(5’-NT/CD73), standard curve range: 14 - 10000 pg/mL
(4-1BBL/TNFSF9), standard curve range: 14 - 10000 pg/mL
(CD226/DNAM-1), standard curve range: 14 - 10000 pg/mL
(CD40), standard curve range: 14 - 10000 pg/mL
(PD-L1), standard curve range: 2.1 - 1500 pg/mL
(IFNγ), standard curve range: 2.7 - 2000 pg/mL
(CD25/IL-2Rα), standard curve range: 21 - 15000 pg/mL
(BTLA), standard curve range: 27 - 20000 pg/mL
(B7-H2/ICOSL), standard curve range: 27 - 20000 pg/mL
(BCA-1/CXCL-13), standard curve range: 3.4 - 2500 ng/mL
(B7-H3/CD276), standard curve range: 3.4 - 2500 ng/mL
(Galectin-1), standard curve range: 34.3 - 25000 pg/mL
(CD80/B7-1), standard curve range: 342 - 250000 pg/mL
(E-Cadherin), standard curve range: 4.1 - 3000 pg/mL
(TNFα), standard curve range: 41 - 30000 pg/mL
(GITR), standard curve range: 41 - 30000 pg/mL
(Galectin-3), standard curve range: 412 - 300000 pg/mL
(LAG-3), standard curve range: 412 - 300000 pg/mL
(TLR-2), standard curve range: 5.5 - 4000 pg/mL
(CD137/4-1BB), standard curve range: 5.5 - 4000 pg/mL
(CTLA-4/CD152), standard curve range: 5.5 - 4000 pg/mL
(TIM-3), standard curve range: 55 - 40000 pg/mL
(CD27), standard curve range: 55 - 40000 pg/mL
(PD-1), standard curve range: 6.9 - 5000 pg/mL
(PD-L2), standard curve range: 8.2 - 6000 pg/mL
(GranzymeB)
detection method
fluorometric (Luminex® xMAP®technology)
shipped in
wet ice
storage temp.
2-8°C
technique(s)
multiplexing: suitable
input
cell lysate
cell culture supernatant
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General description
Application
Analytes included: 4-1BBL/TNFSF9, 5′-NT/CD73, B7-H2/ICOSL, B7-H3/CD276, BCA-1/CXCL-13, BTLA, CD137/4-1BB, CD226/DNAM-1, CD25/IL-2Rα, CD27, CD40, CD80/B7-1, CTLA-4/CD152, E-cadherin, Galectin-1, Galectin-3, GITR, Granzyme B, HVEM, IFNγ, IL-10, LAG-3, PD-1, PD-L1, PD-L2, TIM-3, TLR-2, and TNFα
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
Improved Data Quality: High sensitivity and specificity lead to more reliable data, which is critical for translational research.
Facilitates Drug Development: Understanding checkpoint protein interactions can aid in the development of more effective immunotherapies.
Supports Biomarker Discovery: Helps identify potential biomarkers for sample stratification in immunotherapy research.
Comprehensive Analysis: Provides a broader view of the immune environment in tumors, aiding in the understanding of tumor-immune interactions.
Legal Information
Disclaimer
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
target_organs
Respiratory Tract
Storage Class
10 - Combustible liquids
wgk
WGK 3
Regulatory Information
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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