Skip to Content
Merck
CN

MCVD1MAG-77K

MILLIPLEX® Mouse Cardiovascular Disease Panel

Configurable Mouse CVD 7-Plex Panel 1

Sign In to View Organizational & Contract Pricing.

About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

MILLIPLEX® Mouse Cardiovascular Disease Panel, Configurable Mouse CVD 7-Plex Panel 1

species reactivity

mouse

manufacturer/tradename

Milliplex®

Quality Level

200

packaging

1 ea of

assay range

accuracy: 88-99%
sensitivity: 0.008 ng/mL
(proMMP-9)
sensitivity: 0.012 ng/mL
(PAI-1 (total))
sensitivity: 0.012 ng/mL
(Pecam-1)
sensitivity: 0.013 ng/mL
(sICAM-1)
sensitivity: 0.033 ng/mL
(sE-Selectin)
sensitivity: 0.039 ng/mL
(Thrombomodulin)
sensitivity: 0.429 ng/mL
(sP-Selectin)
standard curve range: 0.007-30 ng/mL
(sICAM-1)
standard curve range: 0.012-50 ng/mL
(proMMP-9)
standard curve range: 0.018-75 ng/mL
(PAI-1 (total))
standard curve range: 0.024-100 ng/mL
(Pecam-1)
standard curve range: 0.024-100 ng/mL
(Thrombomodulin)
standard curve range: 0.049-200 ng/mL
(sE-Selectin)
standard curve range: 0.439-1800 ng/mL
(sP-Selectin)
inter-assay cv: <15%
intra-assay cv: <10%

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 7 analytes in mouse serum, plasma, or cell culture supernatants.

Analytes Included: sCD31/sPECAM-1, sE-Selectin, sICAM-1, PAI-1 (total), ProMMP-9, sP-Selectin, Thrombomodulin

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Features:
  • Targets biomarkers involved in endothelial activation, coagulation, and vascular inflammation
  • Includes 7 analytes relevant to mouse cardiovascular health and immune response
  • Multiplex format enables simultaneous detection from minimal sample volume
  • Compatible with mouse serum, plasma, and cell/tissue culture supernatants
  • Designed for research in atherosclerosis, thrombosis, and vascular injury models

Benefits:
  • Provides a focused profile of vascular and inflammatory biomarkers in mouse models
  • Supports investigation of endothelial dysfunction and cardiovascular disease mechanisms
  • Facilitates evaluation of therapeutic interventions and disease progression
  • Enables high-throughput analysis with reduced sample and reagent use
  • Delivers reproducible, sensitive results for preclinical and translational research

General description

Cardiovascular disease in mouse models is driven by inflammatory and vascular remodeling processes. This panel—sCD31/sPECAM-1, sE-Selectin, sICAM-1, PAI-1 (total), ProMMP-9, sP-Selectin, and Thrombomodulin—captures key indicators of endothelial activation, coagulation, and vascular injury. The MILLIPLEX® Mouse CVD Panel 1 enables multiplexed quantification of these biomarkers in mouse serum or plasma, supporting preclinical research in atherosclerosis, thrombosis, and vascular inflammation.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Regulatory Information

新产品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ulrike Kogel et al.
Journal of applied toxicology : JAT, 41(10), 1598-1619 (2021-04-08)
Cigarette smoking is one major modifiable risk factor in the development and progression of chronic obstructive pulmonary disease and cardiovascular disease. To characterize and compare cigarette smoke (CS)-induced disease endpoints after exposure in either whole-body (WB) or nose-only (NO) exposure
K Monica Lee et al.
Inhalation toxicology, 30(13-14), 553-567 (2019-03-09)
We compared early biological changes in mice after inhalation exposures to cigarette smoke or e-vapor aerosols (MarkTen® cartridge with Carrier, Test-1, or Test-2 formulations; 4% nicotine). Female C57BL/6 mice were exposed to 3R4F cigarette smoke or e-vapor aerosols by nose-only
Lucie Aumailley et al.
Aging, 8(3), 458-483 (2016-02-29)
Suboptimal intake of dietary vitamin C (ascorbate) increases the risk of several chronic diseases but the exact metabolic pathways affected are still unknown. In this study, we examined the metabolic profile of mice lacking the enzyme gulonolactone oxidase (Gulo) required
Lucie Aumailley et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(7), 3623-3640 (2018-02-18)
Werner syndrome (WS) is a premature aging disorder caused by mutations in a RecQ-family DNA helicase (WRN). Mice lacking part of the helicase domain of the WRN ortholog exhibit several phenotypic features of WS. In this study, we generated a
Lucie Aumailley et al.
PloS one, 10(10), e0140292-e0140292 (2015-10-09)
Werner syndrome (WS) is a premature aging disorder caused by mutations in a RecQ-family DNA helicase, WRN. Mice lacking part of the helicase domain of the WRN orthologue exhibit many phenotypic features of WS, including metabolic abnormalities and a shorter
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service