OP134
Anti-IKKβ Mouse mAb (10AG2)
liquid, clone 10AG2, Calbiochem®
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About This Item
UNSPSC Code:
12352203
Clone:
10AG2, monoclonal
Species reactivity:
human
Application:
—
Citations:
2
biological source
mouse
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
10AG2, monoclonal
form
liquid
contains
≤0.1% sodium azide as preservative
species reactivity
human
manufacturer/tradename
Calbiochem®
storage condition
do not freeze
isotype
IgG1
shipped in
wet ice
Quality Level
Gene Information
human ... IKBKB(3551)
target post-translational modification
unmodified
General description
Immunoaffinity purified mouse monoclonal antibody. Recognizes the ~87 kDa IKKβ protein.
Recognizes the ~87 kDa IKKβ protein in Daudi cells.
This Anti-IKKβ Mouse mAb (10AG2) is validated for use in Immunoblotting for the detection of IKKβ.
Immunogen
Human
a recombinant protein consisting of full-length human IKKβ fused to a His•Tag sequence
Application
Immunoblotting (1-4 g/ml, chemiluminescence)
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In PBS, 0.2% gelatin, pH 7.4.
Analysis Note
Positive Control
Daudi cells
Daudi cells
Other Notes
Antibody should be titrated for optimal results in individual systems.
Delhase, M., et al. 1999. Science284, 309.
Li. Q., et al. 1999. Science284, 321.
Didonato, et al. 1997. Nature388, 548.
Lee, F.S., et al. 1997. Cell88, 213.
Malinin, N.L., et al. 1997. Nature385, 540.
Mercurio, F., et al. 1997. Science278, 860.
Regnier, C.H., et al. 1997. Cell90, 373.
Verma, I. And Stevenson, J.K. 1997. Proc. Nat. Acad. Sci. USA94, 11758.
Verma, I.M., et al. 1995. Genes. Dev.9, 2723.
Li. Q., et al. 1999. Science284, 321.
Didonato, et al. 1997. Nature388, 548.
Lee, F.S., et al. 1997. Cell88, 213.
Malinin, N.L., et al. 1997. Nature385, 540.
Mercurio, F., et al. 1997. Science278, 860.
Regnier, C.H., et al. 1997. Cell90, 373.
Verma, I. And Stevenson, J.K. 1997. Proc. Nat. Acad. Sci. USA94, 11758.
Verma, I.M., et al. 1995. Genes. Dev.9, 2723.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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Storage Class
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
新产品
This item has
Certificates of Analysis (COA)
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Jonathan M Starkey et al.
Diabetes, 55(5), 1252-1259 (2006-04-29)
Evidence of diabetes-induced nuclear factor-kappaB (NF-kappaB) activation has been provided with DNA binding assays or nuclear localization with immunohistochemistry, but few studies have explored mechanisms involved. We examined effects of diabetes on proteins comprising NF-kappaB canonical and noncanonical activation pathways
Tamara P Martin et al.
Cellular signalling, 51, 166-175 (2018-07-31)
Calcium/calmodulin dependent protein kinase IIδ (CaMKIIδ) acts as a molecular switch regulating cardiovascular Ca2+ handling and contractility in health and disease. Activation of CaMKIIδ is also known to regulate cardiovascular inflammation and is reported to be required for pro-inflammatory NF-κB
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