OP188
Anti-FAP Mouse mAb (F11-24)
liquid, clone F11-24, Calbiochem®
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
F11-24, monoclonal
Species reactivity:
human
Application:
—
Citations:
3
biological source
mouse
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
F11-24, monoclonal
form
liquid
does not contain
preservative
species reactivity
human
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
dilution
(Flow Cytometry
Frozen Sections (1-5 µg/mL)
Immunoprecipitation )
isotype
IgG1
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... FAP(2191)
General description
Anti-FAP, mouse monoclonal, clone F11-24, recognizes fibroblast activation protein in human. It is validated for use in flow cytometry, immunoprecipitation, & immunohistochemistry (frozen sections).
Protein A purified mouse monoclonal antibody. Recognizes human fibroblast activation protein (FAP).
Recognizes fibroblast activation protein (FAP).
Immunogen
HEK293 cells transfected with an expression vector encoding full-length human FAP
Human
Application
Flow Cytometry (see comments)
Frozen Sections (1-5 µg/ml)
Immunoprecipitation (see comments)
Frozen Sections (1-5 µg/ml)
Immunoprecipitation (see comments)
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In PBS.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Analysis Note
Positive Control
Reactive human fibroblasts, glucagon-producing A cells
Reactive human fibroblasts, glucagon-producing A cells
Other Notes
Does not react with resting fibroblasts of normal organ mesenchyme or parenchymal cells, except for the glucagon-producing A cells found in the pancreatic islets. This antibody has also been reported to work for flow cytometry and immunoprecipitation. Antibody should be titrated for optimal results in individual systems.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Larissa Belov et al.
Methods in molecular biology (Clifton, N.J.), 1619, 263-301 (2017-07-05)
DotScan antibody microarrays were initially developed for the extensive surface profiling of live leukemia and lymphoma cells. DotScan's diagnostic capability was validated with an extensive clinical trial using mononuclear cells from the blood or bone marrow of leukemia or lymphoma
Sarah M Ridge et al.
International journal of cancer, 142(10), 2056-2067 (2017-12-22)
Mesenchymal stem cells (MSCs) are a heterogeneous population of multipotent cells that are capable of differentiating into osteocytes, chondrocytes and adipocytes. Recently, MSCs have been found to home to the tumour site and engraft in the tumour stroma. However, it
Marta Trüb et al.
Journal for immunotherapy of cancer, 8(2) (2020-07-04)
The costimulatory receptor 4-1BB (CD137, TNFRSF9) plays an important role in sustaining effective T cell immune responses and is investigated as target for cancer therapy. Systemic 4-1BB directed therapies elicit toxicity or low efficacy, which significantly hampered advancement of 4-1BB-based
Global Trade Item Number
| SKU | GTIN |
|---|---|
| OP188-100UG | 04055977208870 |