PC41
Anti-Cathepsin B (Ab-3) Rabbit pAb
liquid, Calbiochem®
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
NACRES:
NA.43
UNSPSC Code:
12352203
Product Name
Anti-Cathepsin B (Ab-3) Rabbit pAb, liquid, Calbiochem®
biological source
rabbit
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
form
liquid
contains
≤0.1% sodium azide as preservative
species reactivity
human
manufacturer/tradename
Calbiochem®
storage condition
do not freeze
dilution
(Immunoblotting (1 µg/mL)
Paraffin Sections (2.5 µg/mL, trypsin pre-treatment required))
isotype
IgG
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Other Notes
Barrett, A.J. and Kirschke, H. 1981. Methods Enzymol.80, 535.
Chan, S.J., et al. Proc. Natl. Acad. Sci. USA83, 7721.
Barrett, A.J. 1987. Trends Biochem. Sci.12, 193.
Sloane, B.F. 1990. in Seminars in Cancer Biology, ed. M. M. Gottesman. Vol. 1(2), 137.
Chan, S.J., et al. Proc. Natl. Acad. Sci. USA83, 7721.
Barrett, A.J. 1987. Trends Biochem. Sci.12, 193.
Sloane, B.F. 1990. in Seminars in Cancer Biology, ed. M. M. Gottesman. Vol. 1(2), 137.
Antibody should be titrated for optimal results in individual systems.
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In 0.05 M sodium phosphate buffer, 0.2% gelatin.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Analysis Note
Positive Control
SK-HEP-1 concentrated conditioned medium or breast carcinoma tissue
SK-HEP-1 concentrated conditioned medium or breast carcinoma tissue
Application
Immunoblotting (1 µg/ml)
Paraffin Sections (2.5 µg/ml, trypsin pre-treatment required)
Paraffin Sections (2.5 µg/ml, trypsin pre-treatment required)
Disclaimer
Toxicity: Standard Handling (A)
General description
Anti-Cathepsin B (Ab-3), rabbit polyclonal, recognizes the ~43 kDa latent and ~31 kDa active forms of cathepsin B in breast carcinoma. It is validated for Western blotting and for paraffin sections.
Purified rabbit polyclonal antibody. Recognizes the ~43 kDa latent and the ~31 kDa active forms of cathepsin B.
Recognizes the ~43 kDa latent and the ~31 kDa active forms of cathepsin B in breast carcinoma tissues.
Immunogen
Human
purified human liver cathepsin B
Not finding the right product?
Try our Product Selector Tool.
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Paola Pellegrini et al.
Autophagy, 10(4), 562-571 (2014-02-05)
Acidic pH is an important feature of tumor microenvironment and a major determinant of tumor progression. We reported that cancer cells upregulate autophagy as a survival mechanism to acidic stress. Inhibition of autophagy by administration of chloroquine (CQ) in combination
Mehrnoosh Saghizadeh et al.
Investigative ophthalmology & visual science, 46(10), 3604-3615 (2005-09-28)
To identify proteinases and growth factors abnormally expressed in human corneas of donors with diabetic retinopathy (DR), additional to previously described matrix metalloproteinase (MMP)-10 and -3 and insulin-like growth factor (IGF)-I. RNA was isolated from 35 normal, diabetic, and DR
Xian Zhang et al.
iScience, 19, 607-622 (2019-08-26)
Transforming growth factor beta (TGF-β) signaling contributes to tissue fibrosis. Here we demonstrate that TGF-β enhances CatS and CatK expression but reduces CatB and CatL expression in mouse kidney tubular epithelial cells (TECs). CatS- and CatK deficiency reduces TEC nuclear
Wenqian Fang et al.
Translational research : the journal of laboratory and clinical medicine, 222, 28-40 (2020-05-22)
Nonalcoholic steatohepatitis (NASH) is a severe form of nonalcoholic fatty liver disease characterized by fat accumulation and inflammation in liver. Yet, the mechanistic insight and diagnostic and therapeutic options of NASH remain incompletely understood. This study tested the roles of
Yixing Wu et al.
Acta neuropathologica communications, 11(1), 132-132 (2023-08-15)
Cathepsin B is a cysteine protease that is implicated in multiple aspects of Alzheimer's disease pathogenesis. The endogenous inhibitor of this enzyme, cystatin B (CSTB) is encoded on chromosome 21. Thus, individuals who have Down syndrome, a genetic condition caused
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service