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Merck
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PCYTMAG-23K

MILLIPLEX® Porcine Cytokine/Chemokine Panel

Configurable Porcine Cytokine/Chemokine 13-Plex Panel

Synonym(s):

Pig cytokine panel, minipig cytokine assay, pig cytokine assay, pig cytokine multiplex panel, swine cytokine panel

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

Key Documents

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species reactivity

pig

Quality Level

200

assay range

accuracy: 92-103%, standard curve range: 0.005-20 ng/mL
(IL-1α), standard curve range: 0.012-50 ng/mL
(IL-8), standard curve range: 0.024-100 ng/mL
(GM-CSF, IL-1ra, IL-2, IL-6, IL-10, IL-12, IL-18 & TNFα), standard curve range: 0.061-250 ng/mL
(IL-4), standard curve range: 0.122-500 ng/mL
(IFNγ & IL-1β)

technique(s)

multiplexing: suitable

input

tissue/cellular lysate
culture supernatant(s)

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

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General description

Porcine cytokines play a vital role in understanding immune responses in pigs, which share physiological and genetic similarities with humans. As a model organism, pigs are increasingly used in biomedical research to study various diseases, vaccine development, and the effects of therapies, owing to their comparable immune system and organ sizes to those of humans. This makes them an invaluable resource for translational research aimed at improving human health outcomes. Additionally, research on porcine cytokines contributes significantly to veterinary medicine and animal health, helping to enhance disease management and treatment strategies in livestock populations.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 13 analytes in porcine serum, plasma, tissue/cell lysates, and cell culture supernatants.

Analytes included: GM-CSF, IFNγ, IL-1α, IL-1β, IL-1Ra, IL-2, IL-4, IL-6, IL-8 (CXCL8), IL-10, IL-12, IL-18, TNF-α

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Comprehensive Biomarker Coverage: Includes 13 critical analytes - GM-CSF, IFNγ, IL-1α, IL-1ra, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, IL-12, IL-18, and TNFα.

Maximize Your Research Investment: Save significant time and cost vs. individual ELISAs, completing comprehensive profiling in hours, not days.

Veterinary and Animal Health Applications: Track immune response in real-time, optimize vaccine efficacy with comprehensive cytokine profiling, and distinguish healthy from infected animals with precision.

Translational Biomedical Research Applications: Leverage pigs′ phsyiological similarity to humans.

Proven Reliability: Trusted by research institutions worldwide.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Regulatory Information

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Azita Mellati et al.
Frontiers in immunology, 13, 850271-850271 (2022-06-21)
Ischaemia-reperfusion injury (IRI) is an inevitable process in transplantation and results in inflammation and immune system activation. Alpha-1 antitrypsin (AAT) has anti-inflammatory properties. Normothermic machine perfusion (NMP) can be used to deliver therapies and may help in assessing the effects
Ruipeng Zhao et al.
International immunopharmacology, 99, 107905-107905 (2021-07-10)
To determine whether idealized anterior cruciate ligament reconstruction (IACL-R) restores normal gait features, and whether inflammatory factors are involved in the pathogenesisof post-traumatic osteoarthritis (PTOA). Fourteen mature female minipigs were allocated to a sham group (n = 7) or an IACL-R group
Turun Song et al.
American journal of translational research, 13(8), 8965-8976 (2021-09-21)
Dyslipidemia aggravates kidney injury distal to atherosclerotic renal artery stenosis (ARAS). Besides dyslipidemia, metabolic syndrome (MetS) also involves development of obesity and insulin-resistance (IR). We hypothesized that concurrent obesity and IR magnify swine stenotic-kidney damage beyond dyslipidemia. Pigs with unilateral
David S Gardner et al.
American journal of physiology. Renal physiology, 310(4), F259-F271 (2015-11-27)
Acute kidney injury (AKI) is a common and serious condition with no specific treatment. An episode of AKI may affect organs distant from the kidney, further increasing the morbidity associated with AKI. The mechanism of organ cross talk after AKI
Jessica A Hiemstra et al.
Physiological reports, 2(6) (2014-06-26)
We recently developed a clinically relevant mini-swine model of heart failure with preserved ejection fraction (HFpEF), in which diastolic dysfunction was associated with increased mitochondrial permeability transition (MPT). Early diastolic function is ATP and Ca(2+)-dependent, thus, we hypothesized chronic low
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