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RTHYMAG-30K

MILLIPLEX® Rat Thyroid Panel

Configurable Rat Thyroid 3-Plex Panel

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000

Key Documents

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Product Name

MILLIPLEX® Rat Thyroid Panel, Configurable Rat Thyroid 3-Plex Panel

packaging

1 ea of

assay range

sensitivity: 2255 pg/mL
(T4)
sensitivity: 284 pg/mL
(T3)
sensitivity: 38 pg/mL
(TSH)
standard curve range: 41-10,000 pg/mL
(TSH & T3)
standard curve range: 823-200,00 pg/mL
(T4)
inter-assay cv: <15%
intra-assay cv: <10%

technique(s)

multiplexing: suitable

input

cell culture supernatant(s)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

species reactivity

rat

manufacturer/tradename

Milliplex®

Quality Level

200

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze thyroid-related biomarkers in rat serum, plasma, or tissue lysate samples.

Analytes Included: TSH, Total T3, Total T4

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Features:

  • Magnetic bead-based multiplex format
  • Measures TSH, Total T3, and Total T4 simultaneously
  • Compatible with Luminex® xMAP® technology
  • Verified for use with rat serum, plasma, and tissue lysates
Benefits:

  • Saves time and resources by analyzing multiple analytes in one assay
  • Provides reliable and reproducible results for thyroid hormone profiling
  • Ideal for endocrine and metabolic research in rodent models
  • Reduces need for multiple ELISA kits

General description

TSH (Thyroid Stimulating Hormone), Total T3 (Triiodothyronine), and Total T4 (Thyroxine) are critical regulators of metabolic activity, growth, and development. TSH stimulates the thyroid gland to produce T3 and T4, which in turn influence energy balance, thermoregulation, and protein synthesis at the cellular level. Monitoring these hormones provides essential insights into thyroid function and endocrine status in rodent models, supporting research in metabolic disorders, hormonal regulation, and toxicology.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Regulatory Information

新产品
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Certificates of Analysis (COA)

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Sujie Ke et al.
JCI insight, 6(16) (2021-07-09)
Thyroid hormone receptor β (THRB) is posttranslationally modified by small ubiquitin-like modifier (SUMO). We generated a mouse model with a mutation that disrupted sumoylation at lysine 146 (K146Q) and resulted in desumoylated THRB as the predominant form in tissues. The
The prospective protective effect of selenium nanoparticles against chromium-induced oxidative and cellular damage in rat thyroid.
Hassanin, KM; Abd El-Kawi, SH; Hashem, KS
International journal of nanomedicine null
Giulia Di Dalmazi et al.
Journal of immunology (Baltimore, Md. : 1950), 202(5), 1350-1362 (2019-01-25)
MYMD-1 is a synthetic derivative of tobacco alkaloids, compounds that possess immunoregulatory properties and have been linked to the epidemiological observation that smoking reduces the odds of developing thyroid Abs and hypothyroidism. To assess the effect and mechanism(s) of the
Rauf Latif et al.
Frontiers in endocrinology, 12, 706101-706101 (2021-07-20)
The synergistic activation of transcription factors can lead to thyroid progenitor cell speciation. We have previously shown in vitro that mouse or human stem cells, expressing the transcription factors NKx2-1 and Pax8, can differentiate into thyroid neo-follicular structures (TFS). We
Anthony R P Verkerke et al.
Nature metabolism, 1(9), 876-885 (2020-05-15)
The biophysical environment of membrane phospholipids affects structure, function, and stability of membrane-bound proteins.1,2 Obesity can disrupt membrane lipids, and in particular, alter the activity of sarco/endoplasmic reticulum (ER/SR) Ca2+-ATPase (SERCA) to affect cellular metabolism.3-5 Recent evidence suggests that transport
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