产品名称
MILLIPLEX® 大鼠甲状腺磁珠面板-内分泌多重检测, Configurable Rat Thyroid 3-Plex Panel
packaging
1 ea of
assay range
sensitivity: 2255 pg/mL
(T4)
sensitivity: 284 pg/mL
(T3)
sensitivity: 38 pg/mL
(TSH)
standard curve range: 41-10,000 pg/mL
(TSH & T3)
standard curve range: 823-200,00 pg/mL
(T4)
inter-assay cv: <15%
intra-assay cv: <10%
technique(s)
multiplexing: suitable
input
cell culture supernatant(s)
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
species reactivity
rat
manufacturer/tradename
Milliplex®
Quality Level
Legal Information
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze thyroid-related biomarkers in rat serum, plasma, or tissue lysate samples.
Analytes Included: TSH, Total T3, Total T4
Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.
Analytes Included: TSH, Total T3, Total T4
Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Features and Benefits
Features:
- Magnetic bead-based multiplex format
- Measures TSH, Total T3, and Total T4 simultaneously
- Compatible with Luminex® xMAP® technology
- Verified for use with rat serum, plasma, and tissue lysates
- Saves time and resources by analyzing multiple analytes in one assay
- Provides reliable and reproducible results for thyroid hormone profiling
- Ideal for endocrine and metabolic research in rodent models
- Reduces need for multiple ELISA kits
General description
TSH (Thyroid Stimulating Hormone), Total T3 (Triiodothyronine), and Total T4 (Thyroxine) are critical regulators of metabolic activity, growth, and development. TSH stimulates the thyroid gland to produce T3 and T4, which in turn influence energy balance, thermoregulation, and protein synthesis at the cellular level. Monitoring these hormones provides essential insights into thyroid function and endocrine status in rodent models, supporting research in metabolic disorders, hormonal regulation, and toxicology.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
法规信息
新产品
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Thyroid hormone receptor β (THRB) is posttranslationally modified by small ubiquitin-like modifier (SUMO). We generated a mouse model with a mutation that disrupted sumoylation at lysine 146 (K146Q) and resulted in desumoylated THRB as the predominant form in tissues. The
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The synergistic activation of transcription factors can lead to thyroid progenitor cell speciation. We have previously shown in vitro that mouse or human stem cells, expressing the transcription factors NKx2-1 and Pax8, can differentiate into thyroid neo-follicular structures (TFS). We
Anthony R P Verkerke et al.
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The biophysical environment of membrane phospholipids affects structure, function, and stability of membrane-bound proteins.1,2 Obesity can disrupt membrane lipids, and in particular, alter the activity of sarco/endoplasmic reticulum (ER/SR) Ca2+-ATPase (SERCA) to affect cellular metabolism.3-5 Recent evidence suggests that transport
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