Key Documents

View All Documentation

TX0279

Tetrahydrofuran

Name: Tetrahydrofuran
Brand: MM

≥99.9% (GC), meets USP/NF, inhibitor-free, OmniSolv^®

Synonym(s):

Tetrahydrofuran, Diethylene oxide, THF, Butylene oxide, Oxolane, Tetramethylene oxide

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₄H₈O

CAS Number:

109-99-9

Molecular Weight:

72.11

EC Index Number:

203-726-8

UNSPSC Code:

12191504

MDL number:

MFCD00005356

Beilstein/REAXYS Number:

102391

Assay:

≥99.9% (GC)

Grade:

HPLC grade

Technique(s):

HPLC: suitable

Bp:

65-67 °C (lit.)

Vapor pressure:

114 mmHg ( 15 °C), 143 mmHg ( 20 °C)

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

Tetrahydrofuran, No Stabilizer, Meets Reagent Specifications for testing USP/NF monographs OmniSolv^®

grade

HPLC grade

Quality Level

100

agency

meets USP/NF

vapor density

2.5 (vs air)

vapor pressure

114 mmHg ( 15 °C), 143 mmHg ( 20 °C)

product line

OmniSolv^®

assay

≥99.9% (GC)

form

liquid

autoignition temp.

610 °F

shelf life

12 mo. (from manufacture date)

expl. lim.

1.8-11.8 %

technique(s)

HPLC: suitable

impurities

≤0.02% Peroxide (as H₂O₂), ≤0.02% Water (H₂O), ≤0.8 μeq/g Titrable acid

evapn. residue

≤2 ppm

color

APHA: ≤10

refractive index

n20/D 1.407 (lit.)

pH

7-8 (20 °C, 200 g/L in H₂O)

bp

65-67 °C (lit.)

mp

−108 °C (lit.)

transition temp

flash point -20 °C

solubility

water: miscible

density

0.889 g/mL at 25 °C (lit.)

UV cutoff

≤212 nm

UV absorption

λ: 225 nm A_max: ≤0.50, λ: 250 nm A_max: ≤0.10, λ: 300 nm A_max: ≤0.005, λ: 212 nm A_max: ≤1.00

application(s)

general analytical

shipped in

ambient

storage temp.

no temp limit

SMILES string

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

Description

General description

Tetrahydrofuran (THF), is a colorless, volatile, heterocyclic saturated cyclic ether characterized by low viscosity and high solubility in various solvents. It is widely used as a polar aprotic, water-miscible organic solvent in various organic synthesis, particularly for reactions involving organometallic compounds and Grignard reagents. Additionally, THF plays an important role as a solvent in the synthesis of many API’s and in polymerization processes.

Application

Tetrahydrofuran is used as solvent

To prepare mobile phase in reversed-phase liquid chromatography
In the preparation of Spin-Coated Polymer Thin Films
In the synthesis of diacetylinic aryloxysilane polymers by polycondensation reaction
In the formation of grignard reagent which is used for organic sythesis

Meets Reagent Specifications for testing USP/NF monographs OmniSolv^®

TX0279P-1 is packaged in poly coated glass bottles

Packaging

M-Bottle for Solvents
As a global leader in lab reagents, we are constantly looking for new ways to optimize the safety of our products. The newly developed 4L solvent bottle design features advanced sealing technology that eliminates leaks to make the handling of solvents safer and more convenient than ever before.
See all the new features here!

is packaged in 1L amber glass bottle

is packaged in 4L amber glass bottle

is packaged in 4L polycoated glass bottle

Preparation Note

Product filtered through a 0.2 μm filter

Analysis Note

Expiration dateExp 12 months from mfg dateAssay (GC)99.9% minColor (APHA)10 maxEvaporation residue2ppm maxFiltered through 0.2 µm filterTo pass testFormClear liquidIdentity (IR-spectrum)ConformsPeroxide (as H2O2)*0.02% maxRefractive index (at 20°C)Titrable acid0.8µeq/g maxUV Abs. at 212 nm1.00AU maxUV Abs. at 225 nm0.50AU maxUV Abs. at 250 nm0.10AU maxUV Abs. at 300 nm0.005AU maxUV Cut-off212nm maxWater (H2O)0.02% max

Legal Information

OMNISOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Still not finding the right product?

Explore all of our products under Tetrahydrofuran, No Stabilizer

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3

signalword

Danger

target_organs

Central nervous system, Respiratory system

supp_hazards

EUH019

Storage Class

3 - Flammable liquids

flash_point_f

-6.2 °F - closed cup

flash_point_c

-21.2 °C - closed cup

Regulatory Information

新产品

This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Comparative performance evaluation and systematic screening of solvents in a range of Grignard reactions

Kadam, Asha and Nguyen, et al.

Green Chemistry, 15, 1880-1888 (2013)

Hollow interior structure of spin-coated polymer thin films revealed by ToF-SIMS three-dimensional imaging

Ren, Xianwen and Weng, et al.

Analytical Chemistry, 84, 8497-8504 (2012)

Retention and mass transfer characteristics in reversed-phase liquid chromatography using a tetrahydrofuran--water solution as the mobile phase

Miyabe, Kanji and Sotoura et al.

Journal of Chromatography A, 919, 231-244 (2001)

View All Related Papers

Global Trade Item Number

SKU	GTIN
TX0279-31	04061839445437
TX0279P-1	04061839445567
TX0279-1	04061839445420
TX0279-6	04061839445512
TX0279-NP20	04061839445536
TX0279-7	04061839445529