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Merck
CN

UFC700308

Centricon® Plus Centrifugal Filter

MWCO 3 kDa, sample volume 15-70 mL, regenerated cellulose membrane

Synonym(s):

Centrifuge concentrator

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About This Item

UNSPSC Code:
41104916
eCl@ss:
36100101
NACRES:
NB.24

Key Documents

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Technical Service
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material

polypropylene cap
polypropylene cup (for concentrate/retentate)
polypropylene cup (for filtrate collection)
polypropylene cup (for sample filter)
regenerated cellulose membrane

Quality Level

400

sterility

non-sterile

product line

Amicon®

feature

holdup volume 75 μL

packaging

pkg of 8 filter

manufacturer/tradename

Amicon® Ultra
Centricon®

parameter

15-70 mL sample volume

technique(s)

protein extraction: suitable
protein purification: suitable
western blot: suitable

L

121 mm

diam.

6 cm

filtration area

19 cm2

working volume

≤70 mL
15—70 mL

pore size

3 kDa MWCO

shipped in

ambient

General description

Filter Type: Ultrafiltration
The Centricon Plus-70 centrifugal filter is a disposable, single-use device designed for rapid processing of aqueous biological solutions in volumes ranging from 15 to 70 mL. It is compatible with swinging-bucket centrifuges only. The Centricon Plus-70 device can concentrate most 70 mL solutions down to 350 μL in just 25 minutes (some solutions may take slightly longer).


•90% typical recovery
•50X to 200X concentration
•Low hold-up volume
•Polypropylene housing minimizes binding
•Deadstop prevents spinning to dryness
•Ready to use. Nothing to assemble


Applications:
•Concentrating and desalting chromatography column eluates
•Concentrating monoclonal antibodies
•Concentrating proteins or viruses from culture supernatants
•Clarifying tissue homogenates and cell lysates
•Buffer exchange or diafiltration

Application

3 kDa cutoff, 15 mL to 70 mL volume

Features and Benefits

Minimum Final Concentrate Volume: 350 µL

Physical form

Color Code: Clear

Legal Information

Amicon is a registered trademark of Merck KGaA, Darmstadt, Germany
CENTRICON is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTRACEL is a registered trademark of Merck KGaA, Darmstadt, Germany

Certificates of Analysis (COA)

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Articles

Concentrating Large Volumes With Centricon® Plus-70 Centrifugal Filter Device

Large-volume centrifugal filter devices are a convenient alternative to stirred cell ultrafiltration devices for purifying proteins from large volumes of solution.

Protein Sample Ultrafiltration

Explore ultrafiltration membrane principles and benefits for protein sample preparation, including solvent exchange and sample concentration.

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