biological source
yeast
form
suspension
specific activity
~350 units/mg protein (At 25 °C with glucose-6-P as the substrate.)
packaging
pkg of 1 mL (5 mg/ml)
manufacturer/tradename
Roche
concentration
≥0.1-1.0 % (w/w)
technique(s)
activity assay: suitable
color
white to yellowish
optimum pH
9.2
solubility
water: miscible
suitability
suitable for UV spectrophotometry and general use
NCBI accession no.
UniProt accession no.
application(s)
life science and biopharma
foreign activity
6-PGDH <0.0100%, CK <0.00100%, GR <0.0100%, HK <0.0100%, PGI <0.00200%, PGluM <0.0100%
shipped in
wet ice
storage temp.
2-8°C
Gene Information
Saccharomyces cerevisiae ... ZWF1(855480)
General description
Glucose-6-phosphate dehydrogenase (G6P DH) has an active dimeric form, whereas its monomeric and tetrameric forms are inactive. At low NADP+ and NADPH levels and under normal conditions, the enzyme exists as equilibrium of tetramers and dimers, whereas at high NADP+ and NADPH levels the equilibrium shifts to inactive tetramers.
Application
Component of cofactor recycling systems for NADPH.
Biochem/physiol Actions
Glucose-6-phosphate dehydrogenase (G6P-DH) is involved in the pentose phosphate pathway. It is responsible for catalysing the oxidation of glucose-6-phosphate (G6P) to gluconolactone-6-phosphate, with NADP+ simultaneously accepting hydrogen to form NADPH, thereby maintaining NADPH levels in cells.
Features and Benefits
Contaminants: <0.001% CK, <0.01% GR, HK, 6-PGDH, and PGluM each, <0.002% PGI each, <0.002% PGI
Approximately 350U/mg at +25°C with glucose-6-phosphate as the substrate.
Physical form
Suspension in 3.2 M ammonium sulfate solution, pH approximately 6
Preparation Note
Activator: Mg2+ (5 to 10 mM)
Other Notes
For life science research only. Not for use in diagnostic procedures.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
does not flash
flash_point_c
does not flash
Regulatory Information
常规特殊物品
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 10127655001 | 04061838667380 |