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About This Item
Linear Formula:
NH2C(=NH)NH2 · HSCN
CAS Number:
Molecular Weight:
118.16
PubChem Substance ID:
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
3563461
MDL number:
form
solid
mol wt
118.16
packaging
pkg of 500 g
manufacturer/tradename
Roche
mp
120-122 °C (lit.)
absorption
≤0.10 at 300 and 410 nm in water at 6 M
shipped in
ambient
storage temp.
20-25°C
SMILES string
SC#N.NC(N)=N
InChI
1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H
InChI key
ZJYYHGLJYGJLLN-UHFFFAOYSA-N
General description
Guanidine thiocyanate is chaotropic salts which lyse cells and along with nuclease binding matrix it is also seen to inhibit nuclease activity during extraction of DNA. It works as a strong RNase inhibitor in extraction buffers.
Application
Suitable as denaturing agent for proteins. Guanidine thiocyanate is a stronger denaturant than guanidine hydrochloride.
Chaotropic agent and strong denaturant; solubilizes cells.
Suitable as denaturing agent for proteins. Guanidine thiocyanate is a stronger denaturant than guanidine hydrochloride.
Features and Benefits
Absorbance: A300 and A410 ≤0.10 (6 M in H2O) each
Formula: CH5N3 x HSCN
Formula: CH5N3 x HSCN
Physical form
Crystals
Other Notes
For life science research only. Not for use in diagnostic procedures.
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Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 4 - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 3 Inhalation - Eye Dam. 1 - Skin Corr. 1C
supp_hazards
Storage Class
8A - Combustible corrosive hazardous materials
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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