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CHAPS-RO

Roche

CHAPS

98% (from N), suitable for dialysis, solubility: >50% (Aqueous solutions)

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Synonym(s):
3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate hydrate, 3-[(3-cholamidopropyl)dimethyl-ammonio]-1-propane sulfonate, 3-[(3-cholamidopropyl)dimethyl-ammonio]-1-propane sulfonate, zwitterionic, Cholamidopropyl-dimethyl-ammonio]-1-propane sulfonate, 3-3-, zwitterionic, cholamidopropyl-dimethyl-ammonio]-1-propane sulfonate, 3-3-, CHAPS
Empirical Formula (Hill Notation):
C32H58N2O7S · xH2O
CAS Number:
331717-45-4
Molecular Weight:
614.88 (anhydrous basis)

description

zwitterionic

Assay

98% (from N)

form

crystals

mol wt

614.88 g/mol (anhydrous basis)

packaging

pkg of 10 g (10810118001)
pkg of 50 g (10810126001)

manufacturer/tradename

Roche

technique(s)

dialysis: suitable

CMC

4 mM

mp

157 °C (dec.) (lit.)

solubility

>50% (Aqueous solutions)

absorption

<0.06% at 278 nm in water at 1 % (w/v) (Ease of removal*: ++
Note:
* Arbitrary scale ranges from ++ to −)

storage temp.

2-8°C

SMILES string

O.C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI

1S/C32H58N2O7S.H2O/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36;/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41);1H2/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-;/m1./s1

InChI key

SJCUTFKCLFLIFE-JWTJKVBLSA-N

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General description

3-[(3-Cholamidopropyl)dimethyl-ammonio]-1-propane sulfonate

Application

Solubilization of membrane proteins. Combines the properties of both the sulfobetaine-type and bile-acid detergents.

Physical form

Crystals

Preparation Note

Working concentration: PAGE: 6.5 to 13 mM
Storage conditions (working solution): Do not store in solution, because precipitation may occur.

Other Notes

For life science research only. Not for use in diagnostic procedures.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 - H315 - H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Mohd Amir F Abdullah et al.
BMC biochemistry, 7, 16-16 (2006-05-24)
Aminopeptidase N (APN) type proteins isolated from several species of lepidopteran insects have been implicated as Bacillus thuringiensis (Bt) toxin-binding proteins (receptors) for Cry toxins. We examined brush border membrane vesicle (BBMV) proteins from the mosquito Anopheles quadrimaculatus to determine

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