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Merck
CN

09-1260

2-Chloroethanol

SAJ special grade, ≥99.0%

Synonym(s):

Ethylene chlorohydrin

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About This Item

Linear Formula:
ClCH2CH2OH
CAS Number:
Molecular Weight:
80.51
EC Number:
203-459-7
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
878139
MDL number:
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InChI key

SZIFAVKTNFCBPC-UHFFFAOYSA-N

InChI

1S/C2H5ClO/c3-1-2-4/h4H,1-2H2

SMILES string

OCCCl

grade

SAJ special grade

vapor density

2.78 (vs air)

vapor pressure

5 mmHg ( 20 °C)

assay

≥99.0%

form

liquid

autoignition temp.

797 °F

expl. lim.

16 %

availability

available only in Japan

refractive index

n20/D 1.441 (lit.)

bp

129 °C (lit.)

mp

−89 °C (lit.)

density

1.201 g/mL at 25 °C (lit.)

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Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Liq. 3 - Met. Corr. 1

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

131.0 °F - closed cup

flash_point_c

55 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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A J Bednar et al.
Journal of hazardous materials, 168(2-3), 1041-1046 (2009-04-07)
Active treatment of BCEE (bis-2-chloroethyl ether) is being currently performed in the on-site Cohansey Aquifer at the Lipari Superfund Site. Remediation of BCEE in the underlying Kirkwood aquifer is being considered, necessitating investigations of BCEE geochemistry in aquifer material from
J L Merdink et al.
Toxicology, 245(1-2), 130-140 (2008-02-05)
Chloral hydrate (CH) is a short-lived intermediate in the metabolism of trichloroethylene (TRI). TRI, CH, and two common metabolites, trichloroacetic acid (TCA) and dichloroacetic acid (DCA) have been shown to be hepatocarcinogenic in mice. To better understand the pharmacokinetics of
Sarah B Appel et al.
The Journal of pharmacology and experimental therapeutics, 318(3), 1137-1145 (2006-06-03)
The dopaminergic neurons of the ventral tegmental area (DA VTA neurons) have been implicated in the reinforcing properties of drugs of abuse, including ethanol (ethyl alcohol). Ethanol increases the spontaneous firing frequency of DA VTA neurons in vitro, in both
Haijun Yang et al.
Toxicology in vitro : an international journal published in association with BIBRA, 25(8), 1638-1643 (2011-07-12)
Occupational trichloroethylene (TCE) exposure could induce generalized skin hypersensitivity reactions complicated with severe liver dysfunctions. Active extracellular matrix degradation and remodeling are involved in the skin hypersensitivity reaction induced by chemical exposure. In the present study, we have compared the
A K Salous et al.
British journal of pharmacology, 158(5), 1395-1404 (2009-10-01)
Alcohol produces its behavioural effects in part due to inhibition of N-methyl-d-aspartate (NMDA) receptors in the CNS. Previous studies have identified amino acid residues in membrane-associated domains 3 (M3) and 4 (M4) of the NMDA receptor that influence ethanol sensitivity.

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