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Ethylenediaminetetraacetic acid iron(III) sodium salt

Name: Ethylenediaminetetraacetic acid iron(III) sodium salt
Brand: SAJ

SAJ special grade, ≥95.0%

Synonym(s):

EDTA iron(III) sodium salt, Edathamil, Komplexon^™ II

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About This Item

Linear Formula:

C₁₀H₁₂N₂NaFeO₈

CAS Number:

15708-41-5

Molecular Weight:

367.05

UNSPSC Code:

12352116

PubChem Substance ID:

329748704

EC Number:

239-802-2

MDL number:

MFCD00078215

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Properties

grade

SAJ special grade

assay

≥95.0%

form

crystalline

availability

available only in Japan

mp

80 °C

solubility

water: 72 g/L at 25 °C

shipped in

ambient

SMILES string

[Na+].[Fe+3].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.Fe.Na/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;/q;+3;+1/p-4

InChI key

MKWYFZFMAMBPQK-UHFFFAOYSA-J

Description

Application

Used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors. Iron-EDTA enhances damage due to reactive oxygen species, such as depletion of reduced glutathione, formation of methemoglobin, and lipid peroxidation.

Legal Information

Komplexon is a trademark of CU Chemie Uetikon AG

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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Maize porridge enriched with a micronutrient powder containing low-dose iron as NaFeEDTA but not amaranth grain flour reduces anemia and iron deficiency in Kenyan preschool children.

Catherine W Macharia-Mutie et al.

The Journal of nutrition, 142(9), 1756-1763 (2012-07-20)

Few studies have evaluated the impact of fortification with iron-rich foods such as amaranth grain and multi-micronutrient powder (MNP) containing low doses of highly bioavailable iron to control iron deficiency anemia (IDA) in children. We assessed the efficacy of maize

Fortification iron as ferrous sulfate plus ascorbic acid is more rapidly absorbed than as sodium iron EDTA but neither increases serum nontransferrin-bound iron in women.

Barbara Troesch et al.

The Journal of nutrition, 141(5), 822-827 (2011-03-25)

The absorption profile of iron fortificants may be a determinant of their ability to generate nontransferrin-bound iron (NTBI) and, thus, their potential safety. Ferrous iron may be absorbed more rapidly than chelated ferric iron, but differences at the fortification level

Equivalent effects on fecal reactive oxygen species generation with oral supplementation of three iron compounds: ferrous sulfate, sodium iron EDTA and iron polymaltose.

Monica N Orozco et al.

Annals of nutrition & metabolism, 60(2), 108-114 (2012-03-15)

In any context of iron supplementation in the prenatal prophylaxis or therapeutic dosage range, a large amount will remain unabsorbed and pass through the intestinal tract into the colonic digesta possibly causing increased oxidation. To compare the generation of fecal

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