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Merck
CN

30-0901

Tetrahydrofuran

≥99.0%, SAJ first grade, contains BHT as stabilizer

Synonym(s):

THF, Butylene oxide, Oxolane, Tetramethylene oxide

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About This Item

Empirical Formula (Hill Notation):
C4H8O
CAS Number:
Molecular Weight:
72.11
UNSPSC Code:
12352005
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
102391
Assay:
≥99.0%
Grade:
SAJ first grade
Bp:
65-67 °C (lit.)
Vapor pressure:
114 mmHg ( 15 °C), 143 mmHg ( 20 °C)
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Product Name

Tetrahydrofuran, SAJ first grade, ≥99.0%

grade

SAJ first grade

vapor density

2.5 (vs air)

vapor pressure

114 mmHg ( 15 °C), 143 mmHg ( 20 °C)

assay

≥99.0%

form

liquid

autoignition temp.

610 °F

contains

BHT as stabilizer

expl. lim.

1.8-11.8 %

availability

available only in Japan

dilution

(for analytical testing)

refractive index

n20/D 1.407 (lit.)

pH

~7

bp

65-67 °C (lit.)

mp

−108 °C (lit.)

density

0.889 g/mL at 25 °C (lit.)

SMILES string

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

Application



  • Buffer systems for environmental toxicology: A study utilized buffer concentrates within a tiered regulatory framework for aquatic risk assessment of pesticides, emphasizing the critical role of standardized buffer systems in maintaining consistent experimental conditions (Santos et al., 2024).


  • Buffer concentrate in pharmaceutical formulations: Buffer concentrates were used in the development of a prolonged permeation in situ gel for Levofloxacin HCl-Salicylic Acid, underlining the importance of buffer systems in drug release modulation and stability (Khaing et al., 2024).


  • Buffer concentrate in diagnostic assays: The formulation of lateral flow devices for the detection of urinary biomarkers in kidney health assessments incorporated buffer concentrates to ensure optimal reagent performance and reaction kinetics (D Souza et al., 2024).




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Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system, Respiratory system

signalword

Danger

supp_hazards

Storage Class

3 - Flammable liquids

flash_point_f

5.9 °F

flash_point_c

-14.5 °C

Regulatory Information

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Ryan D Pensack et al.
Journal of the American Chemical Society, 137(21), 6790-6803 (2015-05-07)
We compare the singlet fission dynamics of five pentacene derivatives precipitated to form nanoparticles. Two nanoparticle types were distinguished by differences in their solid-state order and kinetics of triplet formation. Nanoparticles that comprise primarily weakly coupled chromophores lack the bulk
Luca Chiari et al.
The Journal of chemical physics, 138(7), 074301-074301 (2013-03-01)
We present total, elastic, and inelastic cross sections for positron and electron scattering from tetrahydrofuran (THF) in the energy range between 1 and 5000 eV. Total cross sections (TCS), positronium formation cross sections, the summed inelastic integral cross sections (ICS)
Crispin Lichtenberg et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(44), 15797-15805 (2015-09-17)
The reactivity of the all-ferrous FeN heterocubane [Fe4 (Ntrop)4 ] (1) with i) Brønsted acids, ii) σ-donors, iii) σ-donors/π-acceptors, and iv) one-electron oxidants has been investigated (trop = 5H-dibenzo[a,d]cyclo-hepten-5-yl). 1 showed self-re-assembling after reactions with i) and proved surprisingly inert in reactions with ii)



Global Trade Item Number

SKUGTIN
30-0901-8-15KG-J04061833411070