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Merck
CN

01913

2-Ethoxyethyl acetate

certified reference material, TraceCERT®

Synonym(s):

1-Acetoxy-2-ethoxyethane, Cellosolve® acetate, Ethylene glycol monoethyl ether acetate

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About This Item

Linear Formula:
CH3COOCH2CH2OC2H5
CAS Number:
111-15-9
Molecular Weight:
132.16
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329747373
EC Number:
203-839-2
Beilstein/REAXYS Number:
1748677
MDL number:
MFCD00009251

Key Documents

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Product Name

2-Ethoxyethyl acetate, certified reference material, TraceCERT®

SMILES string

CCOCCOC(C)=O

InChI

1S/C6H12O3/c1-3-8-4-5-9-6(2)7/h3-5H2,1-2H3

InChI key

SVONRAPFKPVNKG-UHFFFAOYSA-N

grade

certified reference material
TraceCERT®

vapor density

4.6 (vs air)

vapor pressure

2 mmHg ( 20 °C)

product line

TraceCERT®

autoignition temp.

715 °F

shelf life

limited shelf life, expiry date on the label

expl. lim.

13 %

storage condition

under inert gas

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.406 (lit.)

bp

156 °C (lit.)

mp

−61 °C (lit.)

density

0.975 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

storage temp.

2-8°C

Quality Level

300

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Legal Information

Cellosolve is a registered trademark of Union Carbide
TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

General description

This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)
2-Ethoxyethyl acetate belongs to ethylene glycol ether class of compounds. It is highly miscible with water and organic solvents. It is mostly used in dyes, coatings, insecticides, soaps and cosmetics. It also has teratogenic effect and is capable to bring about testicular changes in rodents.
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3 - Repr. 1B

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

129.2 °F - closed cup

flash_point_c

54 °C - closed cup

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

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D Guest et al.
Environmental health perspectives, 57, 177-183 (1984-08-01)
A comparison was made of the absorption and elimination rates of 2-propoxyethyl acetate (PEA) and 2-ethoxyethyl acetate (EEA) following inhalation, dermal application or IV administration. Male beagle dogs were exposed to 50 ppm PEA or EEA for 5 hr, and
Y Kim et al.
Occupational and environmental medicine, 56(6), 378-382 (1999-09-04)
To evaluate exposure to mixed solvents containing ethylene glycol monoethyl ether acetate (EGEEA) in shipyard painters, to determine if EGEEA is toxic to the bone marrow. An industrial hygiene survey was performed to identify exposure to EGEEA of two groups
S E Chia et al.
American journal of industrial medicine, 31(2), 148-152 (1997-02-01)
The objectives of this study were to determine the exposure levels among workers who handle 2-ethoxyethylacetate (EGEEA) in the liquid crystal display (LCD) manufacturing industry and to study the menstrual patterns among the exposed workers compared to a referent group
B D Hardin et al.
Environmental health perspectives, 57, 69-74 (1984-08-01)
Previous NIOSH studies demonstrated the embryo- and fetotoxicity and teratogenicity of ethylene glycol monoethyl ether (EGEE) applied to the shaved skin of pregnant rats. In the present study ethylene glycol monoethyl ether acetate (EGEEA), ethylene glycol monobutyl ether (EGBE), and
R Vincent et al.
International archives of occupational and environmental health, 65(6), 377-380 (1994-01-01)
The exposure of workers to methylene chloride and phenol in an aeronautical workshop was measured during stripping of paint from a Boeing B 747. Methylene chloride exposure was measured during two work days by personal air sampling, while area sampling
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