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Merck
CN

01913

2-Ethoxyethyl acetate

certified reference material, TraceCERT®

Synonym(s):

1-Acetoxy-2-ethoxyethane, Cellosolve® acetate, Ethylene glycol monoethyl ether acetate

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About This Item

Linear Formula:
CH3COOCH2CH2OC2H5
CAS Number:
111-15-9
Molecular Weight:
132.16
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329747373
EC Number:
203-839-2
Beilstein/REAXYS Number:
1748677
MDL number:
MFCD00009251

Key Documents

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SMILES string

CCOCCOC(C)=O

InChI

1S/C6H12O3/c1-3-8-4-5-9-6(2)7/h3-5H2,1-2H3

InChI key

SVONRAPFKPVNKG-UHFFFAOYSA-N

grade

certified reference material, TraceCERT®

vapor density

4.6 (vs air)

vapor pressure

2 mmHg ( 20 °C)

product line

TraceCERT®

autoignition temp.

715 °F

shelf life

limited shelf life, expiry date on the label

expl. lim.

13 %

storage condition

under inert gas

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

Quality Level

300

bp

156 °C (lit.)

mp

−61 °C (lit.)

density

0.975 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

storage temp.

2-8°C

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General description

2-Ethoxyethyl acetate belongs to ethylene glycol ether class of compounds. It is highly miscible with water and organic solvents. It is mostly used in dyes, coatings, insecticides, soaps and cosmetics. It also has teratogenic effect and is capable to bring about testicular changes in rodents.
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.
This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany
Cellosolve is a registered trademark of Union Carbide

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Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3 - Repr. 1B

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

129.2 °F - closed cup

flash_point_c

54 °C - closed cup

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

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J E Doe
Environmental health perspectives, 57, 33-41 (1984-08-01)
An inhalation teratology study was conducted in rats at 10, 50 and 250 ppm ethylene glycol monoethyl ether (EGEE) and in rabbits at 10, 50 and 175 ppm EGEE. This study was designed to supplement a study conducted for NIOSH
L M Sweeney et al.
Toxicological sciences : an official journal of the Society of Toxicology, 62(1), 124-139 (2001-06-16)
Methoxyethanol (ethylene glycol monomethyl ether, EGME), ethoxyethanol (ethylene glycol monoethyl ether, EGEE), and ethoxyethyl acetate (ethylene glycol monoethyl ether acetate, EGEEA) are all developmental toxicants in laboratory animals. Due to the imprecise nature of the exposure data in epidemiology studies
Reproductive toxicity of ethylene glycol monomethyl ether, ethylene glycol monoethyl ether and their acetates.
J A Wess
Scandinavian journal of work, environment & health, 18 Suppl 2, 43-45 (1992-01-01)
Y Kim et al.
Occupational and environmental medicine, 56(6), 378-382 (1999-09-04)
To evaluate exposure to mixed solvents containing ethylene glycol monoethyl ether acetate (EGEEA) in shipyard painters, to determine if EGEEA is toxic to the bone marrow. An industrial hygiene survey was performed to identify exposure to EGEEA of two groups
S E Chia et al.
American journal of industrial medicine, 31(2), 148-152 (1997-02-01)
The objectives of this study were to determine the exposure levels among workers who handle 2-ethoxyethylacetate (EGEEA) in the liquid crystal display (LCD) manufacturing industry and to study the menstrual patterns among the exposed workers compared to a referent group
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