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Merck
CN

03322

Tartrazine

analytical standard

Synonym(s):

Acid Yellow 23

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About This Item

Empirical Formula (Hill Notation):
C16H9N4Na3O9S2
CAS Number:
1934-21-0
Molecular Weight:
534.36
UNSPSC Code:
85151701
NACRES:
NA.24
E Number:
E102
PubChem Substance ID:
329747588
EC Number:
217-699-5
MDL number:
MFCD00148908
Colour Index Number:
19140
Beilstein/REAXYS Number:
69850

Key Documents

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Product Name

Tartrazine, analytical standard

InChI

1S/C16H12N4O9S2.3Na/c21-15-13(18-17-9-1-5-11(6-2-9)30(24,25)26)14(16(22)23)19-20(15)10-3-7-12(8-4-10)31(27,28)29;;;/h1-8,13H,(H,22,23)(H,24,25,26)(H,27,28,29);;;/q;3*+1/p-3

SMILES string

[Na+].[Na+].[Na+].[O-]C(=O)C1=NN(c2ccc(cc2)S([O-])(=O)=O)C(=O)C1N=Nc3ccc(cc3)S([O-])(=O)=O

InChI key

UJMBCXLDXJUMFB-UHFFFAOYSA-K

grade

analytical standard

assay

≥97.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

Quality Level

100

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Application

Tartrazine may be used as reference standard for the determination of tartrazine in commercial soft drinks using thin layer chromatography and ion-pair high performance liquid chromatography.

General description

Tartrazine is a synthetic azo dye, commonly found in drugs, food products and cosmetics. It can be synthesized by the reaction of sulfanilic acid with 3-carboxy-l-(4-sulfophenyl)-5-pyrazolone.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 1

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL1683
BCBS2174V
BCCG6208

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Determination of synthetic food dyes in commercial soft drinks by TLC and ion-pair HPLC.
Andrade DIF, et al.
Food Chemistry, 157(8), 193-198 (2014)
Simultaneous analysis of tartrazine and its intermediates by reversed phase liquid chromatography.
Wittmer PD, et al.
Am. Fam. Physician., 47(8), 1422-1423 (1975)
Sheng Tian Huang et al.
Chemical communications (Cambridge, England), 48(5), 747-749 (2011-11-29)
We introduce a sensitive, rapid, label-free and general fluorescent method for the determination of tartrazine by competitive binding to reduced graphene oxide (rGO) against fluorescein, and the fluorescence recovery upon fluorescein desorption from rGO provides a quantitative readout for tartrazine
Jing Wang et al.
Journal of biochemical and molecular toxicology, 26(9), 360-367 (2012-07-19)
Acid yellow 23 (AY23) is a pervasive azo dye used in many fields which is potentially harmful to the environment and human health. This paper studied the toxic effects of AY23 on trypsin by spectroscopic and molecular docking methods. The
Drug rash induced by levothyroxine tablets.
Young Hwan Choi et al.
Thyroid : official journal of the American Thyroid Association, 22(10), 1090-1090 (2012-09-12)
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