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Merck
CN

03600585

Luteolin 7-glucoside

primary reference standard

Synonym(s):

Luteolin 7-O-β-D-glucoside, 3′,4′,5,7-Tetrahydroxyflavone 7-glucoside, Cynaroside, Glucoluteolin, Glucosylluteolin, Luteoloside

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About This Item

Empirical Formula (Hill Notation):
C21H20O11
CAS Number:
5373-11-5
Molecular Weight:
448.38
NACRES:
NA.24
PubChem Substance ID:
329747741
UNSPSC Code:
85151701
EC Number:
226-365-8
MDL number:
MFCD06799436

Key Documents

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Product Name

Luteolin 7-glucoside, primary reference standard

InChI key

PEFNSGRTCBGNAN-QNDFHXLGSA-N

InChI

1S/C21H20O11/c22-7-16-18(27)19(28)20(29)21(32-16)30-9-4-12(25)17-13(26)6-14(31-15(17)5-9)8-1-2-10(23)11(24)3-8/h1-6,16,18-25,27-29H,7H2/t16-,18-,19+,20-,21-/m1/s1

SMILES string

OC[C@H]1O[C@@H](Oc2cc(O)c3C(=O)C=C(Oc3c2)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@@H]1O

grade

primary reference standard

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

application(s)

food and beverages

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Related Categories

Application

Reference Standard in the analysis of herbal medicinal products

General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Other Notes

This compound is commonly found in plants of the genus: achillea crataegus humulus hypericum melissa mentha pimpinella salvia thymus

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
HWI01690-4
HWI01690-3
HWI01690-2
HWI01690-1
HWI00806-1

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Donatella Negro et al.
Journal of food science, 77(2), C244-C252 (2012-01-19)
Polyphenol compounds, particularly caffeoylquinic acids and flavonoids, were measured in different tissues and developmental stages of 6 artichoke varietal types diffused in the Mediterranean region. Flower heads were subdivided into external, intermediate, internal bracts, and receptacle, while leaves were collected
Rameshwar U Kadam et al.
Journal of medicinal chemistry, 50(25), 6337-6342 (2007-11-09)
The target for the anti-inflammatory natural products like amentoflavone ( 2), which act by interfering with the proinflammatory cytokine pathway (e.g., TNF-alpha, IL-1beta, and NO synthase), is not yet well-defined. Data obtained from docking, electronic, and surface analyses shed some
Xiao Sun et al.
Journal of cellular biochemistry, 112(8), 2019-2029 (2011-03-30)
Flavonoids with potent anti-oxidative effects are the major effective components in traditional herbal medicine used in treating cardiovascular diseases. Cynaroside is a flavonoid compound that exhibits anti-oxidative capabilities. However, little is known about its effect on oxidative injury to cardiac
Meihua Jin et al.
Biological & pharmaceutical bulletin, 32(9), 1500-1503 (2009-09-02)
Previously, we reported that an ethanol extract of Ailanthus altissima has antiinflammatory activity in an ovalbumin (OVA)-sensitized murine asthmatic model. To determine the biological compounds from this plant, luteolin-7-O-glucoside (L7G) was isolated and its antiasthmatic activity was evaluated in an
Zheng-Ming Qian et al.
Biomedical chromatography : BMC, 21(6), 649-654 (2007-03-21)
This study presents a new HPLC method for the simultaneous determination of seven major components, namely chlorogenic acid, caffeic acid, loganin, sweroside, secoxyloganin, rutin and luteolin 7-O-glucoside in Caulis Lonicerae Japonicae, a commonly used traditional Chinese medicinal herb derived from
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