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03620

Ethylenediaminetetraacetic acid

Name: Ethylenediaminetetraacetic acid
Brand: SIAL

≥98.0% (KT), powder

Synonym(s):

(Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid

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About This Item

Linear Formula:

(HO₂CCH₂)₂NCH₂CH₂N(CH₂CO₂H)₂

CAS Number:

60-00-4

Molecular Weight:

292.24

NACRES:

NA.21

PubChem Substance ID:

329747743

eCl@ss:

39030907

UNSPSC Code:

12352100

EC Number:

200-449-4

MDL number:

MFCD00003541

Beilstein/REAXYS Number:

1716295

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Product Name

Ethylenediaminetetraacetic acid, ≥98.0% (KT)

Quality Level

200

assay

≥98.0% (KT)

form

powder

mp

250 °C (dec.) (lit.)

solubility

water: soluble 0.4 g/L at 20 °C

functional group

amine, carboxylic acid

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

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Acids for Laboratory, Analysis, and Regulated Applications

General description

Ethylenediaminetetraacetic acid (EDTA, N,N,N′,N′-ethylenediaminetetraacetic acid) is a chelating agent. It forms complexes with rare earth metal ions and the stability constants of these complexes have been evaluated. Hydroxyl radicals generated pulse radiolytically in N₂O- and N₂O-O₂-saturated solutions reacts with EDTA. Absorption spectrum of this reaction was recorded and maxima was observed at 275 and 480nm. EDTA is an excellent ligand for Cd(II) and forms stable Cd-EDTA complexes. ¹¹³Cd NMR studies of Cd-EDTA complexes have been reported.

Application

Ethylenediaminetetraacetic acid (EDTA) may be employed in a microtiter plate assay. In this assay, interaction between EDTA or lactoferrin and nisin, lysozyme, or monolaurin against Listeria monocytogenes, Escherichia coli, Salmonella enteritidis, and Pseudomonas fluorescens strains was investigated.

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Warning

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

target_organs

Respiratory Tract

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Irrit. 2 - STOT RE 2 Inhalation

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The stability of the rare earth complexes with ethylenediaminetetraacetic acid.

Wheelwright EJ, et al.

Journal of the American Chemical Society, 75(17), 4196-4201 (1953)

Hobel B and von Sonntag C.

J. Chem. Soc. Perkin Trans. II, 3, 509-514 (1998)

Enhancement of nisin, lysozyme, and monolaurin antimicrobial activities by ethylenediaminetetraacetic acid and lactoferrin.

Jill K Branen et al.

International journal of food microbiology, 90(1), 63-74 (2003-12-16)

A microtiter plate assay was employed to systematically assess the interaction between ethylenediaminetetraacetic acid (EDTA) or lactoferrin and nisin, lysozyme, or monolaurin against strains of Listeria monocytogenes, Escherichia coli, Salmonella enteritidis, and Pseudomonas fluorescens. Low levels of EDTA acted synergistically

Cadmium-113 nuclear magnetic resonance studies of cadmium-ethylenediaminetetraacetic acid complexes.

Jensen CF, et al.

Journal of the American Chemical Society, 103(13), 3659-3666 (1981)

Dipyridyl thiosemicarbazone chelators with potent and selective antitumor activity form iron complexes with redox activity.

Des R Richardson et al.

Journal of medicinal chemistry, 49(22), 6510-6521 (2006-10-27)

There has been much interest in the development of iron (Fe) chelators for the treatment of cancer. We developed a series of di-2-pyridyl ketone thiosemicarbazone (HDpT) ligands which show marked and selective antitumor activity in vitro and in vivo. In

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Global Trade Item Number

SKU	GTIN
E-075-1ML	04061833592762
E1700000	04061833793312
1255001-200MG	04061838723604
PHR1535-500MG	04061834420903
BP860	04061835278640
E9750-25G	04061833609170
E9750-1G	04061835556779
E9750-500MG	04061833609187
E9750-5G	04061833609194
46573-250MG	04061832357263
03620-50G	04061838619037
03620-250G	04061838619020
03620-1KG	04061838619013

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