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Merck
CN

03755

(S)-2-Fmoc-1,2,3,4-tetrahydronorharmane-3-carboxylic acid

≥98.0%

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About This Item

Empirical Formula (Hill Notation):
C27H22N2O4
CAS Number:
Molecular Weight:
438.47
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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assay

≥98.0%

optical activity

[α]20/D +56±2°, c = 1% in DMF

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

OC(=O)[C@@H]1Cc2c(CN1C(=O)OCC3c4ccccc4-c5ccccc35)[nH]c6ccccc26

InChI

1S/C27H22N2O4/c30-26(31)25-13-21-20-11-5-6-12-23(20)28-24(21)14-29(25)27(32)33-15-22-18-9-3-1-7-16(18)17-8-2-4-10-19(17)22/h1-12,22,25,28H,13-15H2,(H,30,31)/t25-/m0/s1

InChI key

IHHULIKSMJSELI-VWLOTQADSA-N



Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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B S Emswiler-Rose et al.
Applied and environmental microbiology, 40(1), 13-18 (1980-07-01)
Staphylococcal food poisoning associated with fermented sausages has been a recurring problem. By testing for thermonuclease by direct application of sausage casing disks on the surface of thermonuclease assay agar plates, possible Staphylococcus aureus growth in fermented sausages could be
Paul R Mueller et al.
Methods in molecular biology (Clifton, N.J.), 296, 299-328 (2004-12-04)
The Wee kinases (Wee1, Wee2, and Myt1) are major regulators of mitotic entry. They function by phosphorylating Cdc2 and related Cdks on conserved tyrosine and threonine residues. This phosphorylation blocks the activity of the Cdc2 and prevents entry into mitosis.
R T Kamakaka et al.
Genes & development, 7(9), 1779-1795 (1993-09-01)
Purified, reconstituted chromatin templates containing regular, physiological nucleosome spacing were transcribed in vitro by RNA polymerase II along with the Gal4-VP16 activator. When Gal4-VP16 was prebound to DNA before reconstitution of either H1-deficient or H1-containing chromatin, the resulting templates were