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03830

Sigma-Aldrich

Ethylene glycol monosalicylate

≥98.0% (GC)

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Synonym(s):
Ethylene glycol salicylate, Salicylic acid 2-hydroxyethyl ester, Salicylic acid ethylene glycol ester
Linear Formula:
HOC6H4COOCH2CH2OH
CAS Number:
87-28-5
Molecular Weight:
182.17
Beilstein:
2255685
EC Number:
201-737-2
MDL number:
MFCD00002862
PubChem Substance ID:
329747823
NACRES:
NA.22

Quality Level

100

Assay

≥98.0% (GC)

form

liquid

refractive index

n20/D 1.548 (lit.)
n20/D 1.549

bp

166 °C/13 mmHg (lit.)

density

1.244 g/mL at 25 °C (lit.)

SMILES string

OCCOC(=O)c1ccccc1O

InChI

1S/C9H10O4/c10-5-6-13-9(12)7-3-1-2-4-8(7)11/h1-4,10-11H,5-6H2

InChI key

LVYLCBNXHHHPSB-UHFFFAOYSA-N

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Related Categories

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

339.8 °F - DIN 51758

Flash Point(C)

171 °C - DIN 51758

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Allergic contact dermatitis from a veterinary antiinflammatory gel containing 2-hydroxyethyl salicylate.
Susana Córdoba et al.
Dermatitis : contact, atopic, occupational, drug, 22(3), 171-172 (2011-05-17)
Contact dermatitis from hydroxyethyl salicylate.
C Reichert et al.
Contact dermatitis, 33(4), 275-276 (1995-10-01)
Miroslav Kucera et al.
Arzneimittel-Forschung, 53(12), 850-856 (2004-01-22)
A combination of the active agents arnica and hydroxyethyl salicylate (HES) in ethanolic solution (Sportino Acute Spray) is cutaneously applied for the treatment of sports injuries and diseases of the locomotor apparatus. The aim was to examine the efficacy and
Contact dermatitis from anti-inflammatory gel containing hydroxyethyl salicylate.
J Horak et al.
Contact dermatitis, 47(2), 120-121 (2002-11-29)
S E Cross et al.
British journal of clinical pharmacology, 46(1), 29-35 (1998-08-05)
The penetration of active ingredients from topically applied anti-inflammatory pharmaceutical products into tissues below the skin is the basis of their therapeutic efficacy. There is still controversy as to whether these agents are capable of direct penetration by diffusion through
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