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Merck
CN

03830

Ethylene glycol monosalicylate

≥98.0% (GC)

Synonym(s):

Ethylene glycol salicylate, Salicylic acid 2-hydroxyethyl ester, Salicylic acid ethylene glycol ester

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About This Item

Linear Formula:
HOC6H4COOCH2CH2OH
CAS Number:
87-28-5
Molecular Weight:
182.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
329747823
EC Number:
201-737-2
Beilstein/REAXYS Number:
2255685
MDL number:
MFCD00002862
Assay:
≥98.0% (GC)
Form:
liquid

Key Documents

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InChI key

LVYLCBNXHHHPSB-UHFFFAOYSA-N

InChI

1S/C9H10O4/c10-5-6-13-9(12)7-3-1-2-4-8(7)11/h1-4,10-11H,5-6H2

SMILES string

OCCOC(=O)c1ccccc1O

assay

≥98.0% (GC)

form

liquid

refractive index

n20/D 1.548 (lit.), n20/D 1.549

bp

166 °C/13 mmHg (lit.)

density

1.244 g/mL at 25 °C (lit.)

Quality Level

100

Related Categories

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

339.8 °F - DIN 51758

flash_point_c

171 °C - DIN 51758

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM7844
BCCL8444
BCCL1716
BCCH1887
BCCH7892

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Miroslav Kucera et al.
Arzneimittel-Forschung, 53(12), 850-856 (2004-01-22)
A combination of the active agents arnica and hydroxyethyl salicylate (HES) in ethanolic solution (Sportino Acute Spray) is cutaneously applied for the treatment of sports injuries and diseases of the locomotor apparatus. The aim was to examine the efficacy and
Contact dermatitis from hydroxyethyl salicylate.
C Reichert et al.
Contact dermatitis, 33(4), 275-276 (1995-10-01)
Contact dermatitis from anti-inflammatory gel containing hydroxyethyl salicylate.
J Horak et al.
Contact dermatitis, 47(2), 120-121 (2002-11-29)
Allergic contact dermatitis from a veterinary antiinflammatory gel containing 2-hydroxyethyl salicylate.
Susana Córdoba et al.
Dermatitis : contact, atopic, occupational, drug, 22(3), 171-172 (2011-05-17)
S E Cross et al.
British journal of clinical pharmacology, 46(1), 29-35 (1998-08-05)
The penetration of active ingredients from topically applied anti-inflammatory pharmaceutical products into tissues below the skin is the basis of their therapeutic efficacy. There is still controversy as to whether these agents are capable of direct penetration by diffusion through
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