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Merck
CN

03835

γ-Aminobutyric acid

analytical standard

Synonym(s):

3-Carboxypropylamine, 4-Aminobutanoic acid, GABA, Piperidic acid, Piperidinic acid

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About This Item

Linear Formula:
NH2(CH2)3COOH
CAS Number:
Molecular Weight:
103.12
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-258-6
Beilstein/REAXYS Number:
906818
MDL number:
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grade

analytical standard

Quality Level

assay

≥97.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

analyte chemical class(es)

amino acids, peptides, proteins

technique(s)

HPLC: suitable

impurities

≤1.0% water

mp

195 °C (dec.) (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

format

neat

SMILES string

NCCCC(O)=O

InChI

1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)

InChI key

BTCSSZJGUNDROE-UHFFFAOYSA-N

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General description

γ-Aminobutyric acid is a chief inhibitory neurotransmitter, which is found in the cerebellum, hypothalamus, thalamus and hippocampus. It is formed via the decarboxylation of L-glutamate catalyzed by the enzyme, glutamic acid decarboxylase(GAD).

Biochem/physiol Actions

Major inhibitory neurotransmitter in brain; GABAA and GABAB receptor agonist; increases Cl conductance.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Wen-Zhao Cui et al.
Biology, 10(9) (2021-09-29)
Diapause is a developmental transition in insects based on seasonal adaptation to adversity; it is regulated by a circadian clock system and the endocrine system. However, the molecular node and its mechanism underlying the effects of these systems are still
Medicinal Chemistry: A Molecular and Biochemical Approach (2005)
Antonela G Garzón et al.
Journal of food science and technology, 55(8), 3188-3198 (2018-08-02)
Two cultivars of sorghum were germinated at 25 or 30 °C for 1, 2, or 3 days to investigate the evolution of γ-Aminobutyric acid (GABA), total free phenolic compounds (FPC), hydroxycinnamic acid derivatives, free amino acid (FAA) profile, and antioxidant activity during
Jaisan Islam et al.
International journal of molecular sciences, 22(16) (2021-08-28)
The nucleus accumbens core (NAcc) is an important component of brain reward circuitry, but studies have revealed its involvement in pain circuitry also. However, its effect on trigeminal neuralgia (TN) and the mechanism underlying it are yet to be fully
Shang-Feng Gao et al.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 17(1), 124-144 (2010-03-20)
Stress response and depression have a significant impact on modern society. Although the symptoms are well characterized, the molecular mechanisms underlying depression are largely unknown. The monoamine hypothesis, which postulates dysfunctional noradrenergic and serotonergic systems as the underlying primary cause

Global Trade Item Number

SKUGTIN
C8210-100G04061833619100
C8210-25G04061833521915
C2885-100G04061833484739
29311-50G04061833448687
239779-100GM07790788048921
C2885-25G04061833484760
V900295-100G04061833469330
V900295-250G04061833503782
3100-100GM04061839403031
29311-10G04061833482216
C2885-250G04061833484753
C2885-1KG04061833484746
03835-250MG04061838628305

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