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04238

Hydroxyapatite

Name: Hydroxyapatite
Brand: SIAL

puriss., meets analytical specification of Ph. Eur., BP, FCC, E341, ≥90% (calculated on glowed substance)

Synonym(s):

Calcium phosphate hydroxide, Durapatite, Hydroxylapatite

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About This Item

Linear Formula:

3Ca₃(PO₄)₂ · Ca(OH)₂

CAS Number:

1306-06-5

Molecular Weight:

502.31

NACRES:

NA.21

PubChem Substance ID:

57646735

UNSPSC Code:

41116107

EC Number:

215-145-7

MDL number:

MFCD00010904

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grade

puriss.

Quality Level

200

assay

≥90% (calculated on glowed substance)

form

powder

quality

meets analytical specification of Ph. Eur., BP, FCC, E341

composition

Ca, 35-40%

impurities

residual solvents, complies, ≤0.001% heavy metals (as Pb), ≤0.2% insoluble in HCl

loss

≤8% loss on ignition, 800 °C

anion traces

chloride (Cl^-): ≤1500 mg/kg, fluoride (F^-): ≤50 mg/kg, sulfate (SO₄^2-): ≤5000 mg/kg

cation traces

As: ≤2 mg/kg, Cd: ≤1 mg/kg, Cu: ≤20 mg/kg, Fe: ≤400 mg/kg, Hg: ≤1 mg/kg, Pb: ≤2 mg/kg, Zn: ≤20 mg/kg

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

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Application

New Physico-Chemical Analysis of Magnesium-Doped Hydroxyapatite in Dextran Matrix Nanocomposites.: This research article focuses on the development and characterization of magnesium-doped hydroxyapatite within a dextran matrix, emphasizing its potential applications in biomedical and tissue engineering fields (Predoi et al., 2023).

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Mechanical properties of sintered hydroxyapatite for prosthetic applications.

Akao M ,et al.

J. Mater. Sci., 16(3), 809-812 (1981)

Structural analysis of hydroxyapatite coatings on titanium.

P Ducheyne et al.

Biomaterials, 7(2), 97-103 (1986-03-01)

Hydroxyapatite from two sources was electrophoretically deposited onto flat titanium plate material. Depending upon the deposition conditions various changes in the structure of the ceramic were identified. A well-adhering Ti-P compound was present at the interface. Hydroxyapatite oxygenated to various

Chemical characterization of silicon-substituted hydroxyapatite

Gibson I, et al.

Journal of Biomedical Materials Research, 44(4), 422-428 (1999)

Macrophage-derived matrix vesicles: an alternative novel mechanism for microcalcification in atherosclerotic plaques.

Sophie E P New et al.

Circulation research, 113(1), 72-77 (2013-04-26)

We previously showed that early calcification of atherosclerotic plaques associates with macrophage accumulation. Chronic renal disease and mineral imbalance accelerate calcification and the subsequent release of matrix vesicles (MVs), precursors of microcalcification. We tested the hypothesis that macrophage-derived MVs contribute

Lower reoperation rate for cemented hemiarthroplasty than for uncemented hemiarthroplasty and internal fixation following femoral neck fracture: 12- to 19-year follow-up of patients aged 75 years or more.

Bjarke Viberg et al.

Acta orthopaedica, 84(3), 254-259 (2013-04-19)

Elderly patients with displaced femoral neck fractures are commonly treated with a hemiarthroplasty (HA), but little is known about the long-term failure of this treatment. We compared reoperation rates for patients aged at least 75 years with displaced femoral neck

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Global Trade Item Number

SKU	GTIN
T206-25G	04061837338830
95320-50G	04061833315927
T206-100G	04061837338823
V900613-500G	04061833042816
95320-250G	04061833039489
95320-10G	04061833039472
8007990100	04022536874128
8007990025	04022536362595
PHR3881-500MG	04065270639912
04238-1KG	04061838629227

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