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Merck
CN

05097

(+)-Sodium L-ascorbate

Synonym(s):

E301; Vitamine C sodium salt, L(+)-Ascorbic acid sodium salt, Vitamin C sodium salt

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About This Item

Empirical Formula (Hill Notation):
C6H7NaO6
CAS Number:
134-03-2
Molecular Weight:
198.11
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329748045
EC Number:
205-126-1
Beilstein/REAXYS Number:
3767246
MDL number:
MFCD00082340

Key Documents

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SMILES string

[Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]

InChI key

PPASLZSBLFJQEF-RXSVEWSESA-M

InChI

1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1

Quality Level

100

assay

≥98.5% (TLC)

shelf life

limited shelf life, expiry date on the label

composition

Na, 10.8-12.8%

loss

≤2.0% loss on drying

mp

220 °C (dec.) (lit.)

application(s)

cleaning products
cosmetics
detection
food and beverages
personal care

format

neat

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General description

(+)-Sodium L-ascorbate is a sodium salt of ascorbic acid.

Application

Sodium ascorbate has been used as a reference standard for the determination of sodium ascorbate in polyvitaminated premixes utilized for the fortification of infant nutrition products by reversed-phase high performance liquid chromatography (RP-HPLC) combined with ultra-violet (UV) detection and in pharmaceutical formulations by RP-ion pair LC method. (+)-Sodium L-ascorbate may be used as an analytical standard for the identification and quantification of (+)-sodium L-ascorbate as a ferric ion chelator (FIC) by HPLC post-column method with fluorescence detection.

Storage Class

11 - Combustible Solids

wgk

WGK 1

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG0239
BCCC1564
BCBX5858
BCBS4496V

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Separation of water-soluble vitamins by reversed-phase high performance liquid chromatography with ultra-violet detection: application to polyvitaminated premixes.
Heudi O, et al.
Journal of Chromatography A, 1070(1-2), 49-56 (2005)
High-performance liquid chromatography method for ferric iron chelators using a post-column reaction with Calcein Blue.
Ariga T, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 985, 48-53 (2015)
M G Gioia et al.
Journal of pharmaceutical and biomedical analysis, 48(2), 331-339 (2008-02-26)
A reversed-phase ion pair liquid chromatographic method (RP-LC) for the determination of dehydroascorbic acid (DHA) and ascorbic acid (AA) and also acetaminophen, which is combined in pharmaceuticals, is proposed and validated. AA and acetaminophen were analyzed directly, while DHA was
Marina A Kozuleva et al.
FEBS letters, 588(23), 4364-4368 (2014-10-15)
O2 reduction was investigated in photosystem I (PSI) complexes isolated from cyanobacteria Synechocystis sp. PCC 6803 wild type (WT) and menB mutant strain, which is unable to synthesize phylloquinone and contains plastoquinone at the quinone-binding site A1. PSI complexes from
Aleksander Hinek et al.
Journal of dermatological science, 75(3), 173-182 (2014-07-13)
Vitamin C (L-ascorbic acid), a known enhancer of collagen deposition, has also been identified as an inhibitor of elastogenesis. Present studies explored whether and how the L-ascorbic acid derivative (+) sodium L-ascorbate (SA) would affect production of collagen and elastic
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