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Merck
CN

05097

(+)-Sodium L-ascorbate

analytical standard

Synonym(s):

E301; Vitamine C sodium salt, L(+)-Ascorbic acid sodium salt, Vitamin C sodium salt

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About This Item

Empirical Formula (Hill Notation):
C6H7NaO6
CAS Number:
Molecular Weight:
198.11
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
205-126-1
Beilstein/REAXYS Number:
3767246
MDL number:
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grade

analytical standard

Quality Level

assay

≥98.5% (TLC)

shelf life

limited shelf life, expiry date on the label

composition

Na, 10.8-12.8%

loss

≤2.0% loss on drying

mp

220 °C (dec.) (lit.)

application(s)

cleaning products
cosmetics
detection
food and beverages
personal care

format

neat

SMILES string

[Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]

InChI

1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1

InChI key

PPASLZSBLFJQEF-RXSVEWSESA-M

General description

(+)-Sodium L-ascorbate is a sodium salt of ascorbic acid.

Application

Sodium ascorbate has been used as a reference standard for the determination of sodium ascorbate in polyvitaminated premixes utilized for the fortification of infant nutrition products by reversed-phase high performance liquid chromatography (RP-HPLC) combined with ultra-violet (UV) detection and in pharmaceutical formulations by RP-ion pair LC method. (+)-Sodium L-ascorbate may be used as an analytical standard for the identification and quantification of (+)-sodium L-ascorbate as a ferric ion chelator (FIC) by HPLC post-column method with fluorescence detection.


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Storage Class

11 - Combustible Solids

wgk

WGK 1



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High-performance liquid chromatography method for ferric iron chelators using a post-column reaction with Calcein Blue.
Ariga T, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 985, 48-53 (2015)
Separation of water-soluble vitamins by reversed-phase high performance liquid chromatography with ultra-violet detection: application to polyvitaminated premixes.
Heudi O, et al.
Journal of Chromatography A, 1070(1-2), 49-56 (2005)
M G Gioia et al.
Journal of pharmaceutical and biomedical analysis, 48(2), 331-339 (2008-02-26)
A reversed-phase ion pair liquid chromatographic method (RP-LC) for the determination of dehydroascorbic acid (DHA) and ascorbic acid (AA) and also acetaminophen, which is combined in pharmaceuticals, is proposed and validated. AA and acetaminophen were analyzed directly, while DHA was



Global Trade Item Number

SKUGTIN
05097-500MG04061838636867